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    usp108 U1 snRNP-associated protein Usp108 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541487, updated on 22-Jun-2024

    Summary

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    Gene symbol
    usp108
    Gene description
    U1 snRNP-associated protein Usp108
    Locus tag
    SPOM_SPAC23D3.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAC23D3.08
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    Genomic context

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    See usp108 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (4352500..4355260)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene nucleoporin, WD repeat Nup146 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene proteasome core particle subunit beta 2 Neighboring gene SWI/SNF and RSC complex subunit Arp42 Neighboring gene ncRNA Neighboring gene cell wall and ascospore endo-1,3-beta-glucanase Eng2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 1-acyldihydroxyacetone phosphate reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of the U1 snRNP of Schizosaccharomyces pombe reveals three essential organism-specific proteins. Newo AN, et al. Nucleic Acids Res, 2007. PMID 17264129, Free PMC Article
    2. Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. Thakran P, et al. EMBO J, 2018 Jan 4. PMID 28947618, Free PMC Article
    3. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
    4. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Egan ED, et al. RNA, 2014 Jun. PMID 24713849, Free PMC Article
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA 5'-splice site recognition IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U1 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    U1 snRNP-associated protein Usp108

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4352500..4355260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019974.4 → NP_594545.2  U1 snRNP-associated protein Usp108 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594545.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09848
      Conserved Domains (2) summary
      cd00105
      Location:288 → 327
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam16134
      Location:16 → 160
      THOC2_N; THO complex subunit 2 N-terminus
    Nucleotide Protein
    Heading Accession and Version

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