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    saf4 splicing-associated factor Saf4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540801, updated on 18-Sep-2024

    Summary

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    Official Symbol
    saf4
    Official Full Name
    splicing-associated factor Saf4
    Primary source
    PomBase:SPBC18H10.10c
    Locus tag
    SPOM_SPBC18H10.10C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See saf4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (1786609..1789046, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene WD repeat-containing protein Neighboring gene Set1C complex subunit Swd2.1 Neighboring gene WW domain-binding protein 4 Neighboring gene ubiquitin hydrolase Ubp4 Neighboring gene zf-CHY type zinc finger protein Neighboring gene ncRNA Neighboring gene PPR repeat-containing protein Ppr2 Neighboring gene RNase MRP subunit, ribosomal protein L7-like Rpl701 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast. Bayne EH, et al. Genome Biol, 2014. PMID 25274039, Free PMC Article
    2. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Livesay SB, et al. Eukaryot Cell, 2013 Nov. PMID 24014766, Free PMC Article
    3. The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast. Kallgren SP, et al. PLoS Genet, 2014. PMID 24874881, Free PMC Article
    4. Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes. Chen W, et al. RNA, 2014 Mar. PMID 24442611, Free PMC Article
    5. Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. Thakran P, et al. EMBO J, 2018 Jan 4. PMID 28947618, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U2-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    part_of post-mRNA release spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing-associated factor Saf4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1786609..1789046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021632.3 → NP_595734.2  splicing-associated factor Saf4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595734.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60141
      Conserved Domains (2) summary
      COG5134
      Location:6 → 265
      COG5134; Uncharacterized conserved protein [Function unknown]
      pfam04502
      Location:7 → 226
      DUF572; Family of unknown function (DUF572)
    Nucleotide Protein
    Heading Accession and Version

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