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    PUL4 Pul4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855800, updated on 17-May-2024

    Summary

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    Gene symbol
    PUL4
    Gene description
    Pul4p
    Primary source
    FungiDB:YNR063W
    Locus tag
    YNR063W
    See related
    SGD:S000005346; AllianceGenome:SGD:S000005346; VEuPathDB:YNR063W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription from RNA polymerase II promoter by galactose. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See PUL4 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (746943..748766)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Pul3p Neighboring gene epoxide hydrolase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional and evolutionary characterization of a secondary metabolite gene cluster in budding yeasts. Krause DJ, et al. Proc Natl Acad Sci U S A, 2018 Oct 23. PMID 30297402, Free PMC Article
    2. Iterative carotenogenic screens identify combinations of yeast gene deletions that enhance sclareol production. Trikka FA, et al. Microb Cell Fact, 2015 Apr 24. PMID 25903744, Free PMC Article
    3. Chromatin remodeling complexes are involvesd in the regulation of ethanol production during static fermentation in budding yeast. Fang T, et al. Genomics, 2020 Mar. PMID 31618673
    4. Phenotypic analysis of genes encoding yeast zinc cluster proteins. Akache B, et al. Nucleic Acids Res, 2001 May 15. PMID 11353088, Free PMC Article
    5. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Badis G, et al. Mol Cell, 2008 Dec 26. PMID 19111667, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pul4p
    NP_014461.3
    • Putative zinc-cluster transcription factor; involved in utilization of iron-transporting siderophore pulcherrimin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      746943..748766
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183240.3 → NP_014461.3  TPA: Pul4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014461.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1N8, P53749
      UniProtKB/TrEMBL
      A0A8H4BXD9, A6ZSD7, B3LPI0, B5VR88, C7GIY3, C8ZFU2
      Conserved Domains (2) summary
      cd12148
      Location:184 → 575
      fungal_TF_MHR; fungal transcription factor regulatory middle homology region
      smart00066
      Location:10 → 47
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53749.1

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