U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    arc4 ARP2/3 actin-organizing complex subunit Arc4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541767, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    arc4
    Official Full Name
    ARP2/3 actin-organizing complex subunit Arc4
    Primary source
    PomBase:SPAC6G9.07c
    Locus tag
    SPOM_SPAC6G9.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    arc19
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See arc4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (3258471..3259484, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene coenzyme A diphosphatase Neighboring gene gamma tubulin complex linker, pericentrin/kendrin Pcp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin hydrolase Ubp6 Neighboring gene 60S ribosomal protein eL24

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Schizosaccharomyces pombe Arc3 is a conserved subunit of the Arp2/3 complex required for polarity, actin organization, and endocytosis. Cabrera R, et al. Yeast, 2011 Jun. PMID 21449051, Free PMC Article
    2. A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast. Morrell JL, et al. Mol Biol Cell, 1999 Dec. PMID 10588653, Free PMC Article
    3. Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit. Nolen BJ, et al. J Biol Chem, 2008 Sep 26. PMID 18640983, Free PMC Article
    4. Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Chavali SS, et al. Nat Commun, 2024 Mar 6. PMID 38448439, Free PMC Article
    5. Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast. Skau CT, et al. J Biol Chem, 2011 Jul 29. PMID 21642440, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables actin filament binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Arp2/3 complex-mediated actin nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Arp2/3 complex-mediated actin nucleation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin cortical patch assembly IC
    Inferred by Curator
    more info
    		  
    involved_in actin filament branching EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in endocytosis IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Arp2/3 protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in actin cortical patch IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ARP2/3 actin-organizing complex subunit Arc4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3258471..3259484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019540.3 → NP_594116.1  ARP2/3 actin-organizing complex subunit Arc4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594116.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q92352, Q9URL0
      Conserved Domains (1) summary
      pfam05856
      Location:1 → 166
      ARPC4; ARP2/3 complex 20 kDa subunit (ARPC4)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.