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    SLC35G1 solute carrier family 35 member G1 [ Homo sapiens (human) ]

    Gene ID: 159371, updated on 2-Nov-2024

    Summary

    Official Symbol
    SLC35G1provided by HGNC
    Official Full Name
    solute carrier family 35 member G1provided by HGNC
    Primary source
    HGNC:HGNC:26607
    See related
    Ensembl:ENSG00000176273 MIM:617167; AllianceGenome:HGNC:26607
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    POST; TMEM20; C10orf60
    Summary
    This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. [provided by RefSeq, Sep 2016]
    Expression
    Biased expression in duodenum (RPKM 26.1), small intestine (RPKM 12.8) and 2 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SLC35G1 in Genome Data Viewer
    Location:
    10q23.33
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (93893978..93909830)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (94773053..94788891)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (95653735..95669587)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378437 Neighboring gene leucine rich glioma inactivated 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:95550082-95550640 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:95609025-95609669 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2630 Neighboring gene RAB11A, member RAS oncogene family pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2631 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:95686691-95687890 Neighboring gene PIP5K1A and PSMD4 like (pseudogene) Neighboring gene uncharacterized LOC105378438

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ33990

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    solute carrier family 35 member G1
    Names
    partner of STIM1
    transmembrane protein 20

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_051626.1 RefSeqGene

      Range
      5009..14855
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001134658.3NP_001128130.1  solute carrier family 35 member G1 isoform 1

      See identical proteins and their annotated locations for NP_001128130.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AK091309, AL138923, BC041432, BC104814
      Consensus CDS
      CCDS44459.1
      UniProtKB/Swiss-Prot
      Q2M3R5, Q86YG5, Q8NBA5
      UniProtKB/TrEMBL
      B7ZKP1
      Related
      ENSP00000400932.1, ENST00000427197.2
      Conserved Domains (1) summary
      COG0697
      Location:70359
      RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    2. NM_001345993.2NP_001332922.1  solute carrier family 35 member G1 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
      Source sequence(s)
      AL138923, BC143283, DA644843
      UniProtKB/TrEMBL
      B7ZKP0
      Conserved Domains (1) summary
      COG0697
      Location:53342
      RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
    3. NM_153226.4NP_694958.1  solute carrier family 35 member G1 isoform 2

      See identical proteins and their annotated locations for NP_694958.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in a protein (isoform 2) that is one amino acid shorter than isoform 1.
      Source sequence(s)
      AK091309, AL138923, BC041432
      Consensus CDS
      CCDS7432.1
      UniProtKB/TrEMBL
      B7ZKP1
      Related
      ENSP00000360462.3, ENST00000371408.7
      Conserved Domains (2) summary
      COG0697
      Location:69358
      RhaT; Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only]
      pfam00892
      Location:68201
      EamA; EamA-like transporter family

    RNA

    1. NR_144335.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) uses an alternate splice site in the 5'-terminal exon, and uses alternate internal and 3' exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AL138923, BC036382, DA644843
      Related
      ENST00000483386.5
    2. NR_144336.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) uses alternate internal and 3' exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AK091309, AL138923, BC047102, BM677569, BU608007, R56424
      Related
      ENST00000603665.1
    3. NR_144337.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) uses alternate internal and 3' exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AL138923

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      93893978..93909830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      94773053..94788891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)