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    CYP2B7P cytochrome P450 family 2 subfamily B member 7, pseudogene [ Homo sapiens (human) ]

    Gene ID: 1556, updated on 17-Sep-2024

    Summary

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    Official Symbol
    CYP2B7Pprovided by HGNC
    Official Full Name
    cytochrome P450 family 2 subfamily B member 7, pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:2616
    See related
    Ensembl:ENSG00000291083 AllianceGenome:HGNC:2616
    Gene type
    pseudo
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CYP2B; CYP2B7; CYP2B7P1
    Expression
    Biased expression in lung (RPKM 25.4), liver (RPKM 15.7) and 3 other tissues See more
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    Genomic context

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    See CYP2B7P in Genome Data Viewer
    Location:
    19q13.2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (40924265..40950660)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (43745020..43771413)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (41430170..41456565)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 2 subfamily A member 7 Neighboring gene Sharpr-MPRA regulatory region 12493 Neighboring gene cytochrome P450 family 2 subfamily G member 1, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10651 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:41426957-41427227 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:41486817-41487680 Neighboring gene XREM-like enhancer of CYP2B6 Neighboring gene CYP2B6 promoter-proximal regulatory region Neighboring gene cytochrome P450 family 2 subfamily B member 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:41532560-41533088 Neighboring gene cytochrome P450 family 2 subfamily A member 7 pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Partial deletion of CYP2B6 owing to unequal crossover with CYP2B7. Rotger M, et al. Pharmacogenet Genomics, 2007 Oct. PMID 17885627
    2. cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver. Yamano S, et al. Biochemistry, 1989 Sep 5. PMID 2573390
    3. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Fernandez-Salguero P, et al. Am J Hum Genet, 1995 Sep. PMID 7668294, Free PMC Article
    4. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Nelson DR, et al. Pharmacogenetics, 2004 Jan. PMID 15128046
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Other Names

    • cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
    • cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
    • cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_001278.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      BC041174
      Related
      ENST00000599198.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      40924265..40950660
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      43745020..43771413
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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