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    FBXW7 F-box and WD repeat domain containing 7 [ Homo sapiens (human) ]

    Gene ID: 55294, updated on 3-Nov-2024

    Summary

    Official Symbol
    FBXW7provided by HGNC
    Official Full Name
    F-box and WD repeat domain containing 7provided by HGNC
    Primary source
    HGNC:HGNC:16712
    See related
    Ensembl:ENSG00000109670 MIM:606278; AllianceGenome:HGNC:16712
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AGO; CDC4; FBW6; FBW7; hAgo; FBX30; FBXW6; SEL10; hCdc4; DEDHIL; FBXO30; SEL-10
    Summary
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
    Expression
    Broad expression in skin (RPKM 23.3), brain (RPKM 19.1) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See FBXW7 in Genome Data Viewer
    Location:
    4q31.3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (152320544..152536092, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (155643699..155859255, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (153241696..153457244, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 446, pseudogene Neighboring gene uncharacterized LOC105377492 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22029 Neighboring gene FBXW7 antisense RNA 1 Neighboring gene VISTA enhancer hs1361 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22030 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22031 Neighboring gene microRNA 3140 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:153437089-153437307 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22032 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:153456939-153457474 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22034 Neighboring gene MIR4453 host gene Neighboring gene microRNA 4453 Neighboring gene RPS3A pseudogene 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ16457, DKFZp686F23254

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables cyclin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cyclin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables phosphothreonine residue binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-macromolecule adaptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ubiquitin-like ligase-substrate adaptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ubiquitin-protein transferase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to UV IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in lipid homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in lung development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of Notch signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of SREBP signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of hepatocyte proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of osteoclast development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of triglyceride biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of ERK1 and ERK2 cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of epidermal growth factor-activated receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of proteasomal protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of protein targeting to mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein destabilization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein stabilization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cell cycle G1/S phase transition TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of cell migration involved in sprouting angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of lipid storage ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of mitophagy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in rhythmic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ubiquitin recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vasculature development TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in vasculogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Parkin-FBXW7-Cul1 ubiquitin ligase complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of SCF ubiquitin ligase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    F-box/WD repeat-containing protein 7
    Names
    F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
    F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)
    F-box protein FBW7
    F-box protein FBX30
    F-box protein SEL-10
    archipelago
    homolog of C elegans sel-10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029466.2 RefSeqGene

      Range
      5782..221330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_1141

    mRNA and Protein(s)

    1. NM_001013415.2NP_001013433.1  F-box/WD repeat-containing protein 7 isoform 3

      See identical proteins and their annotated locations for NP_001013433.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (3) is shorter and has a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC080078, AY049984, BX498391, BX502790
      Consensus CDS
      CCDS34078.1
      UniProtKB/TrEMBL
      A0A994J497
      Related
      ENSP00000296555.4, ENST00000296555.11
      Conserved Domains (4) summary
      COG2319
      Location:249589
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:256532
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam12937
      Location:163207
      F-box-like; F-box-like
      sd00039
      Location:266301
      7WD40; WD40 repeat [structural motif]
    2. NM_001257069.1NP_001243998.1  F-box/WD repeat-containing protein 7 isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 4 which is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      BC014503, HQ873866
      Consensus CDS
      CCDS64082.1
      UniProtKB/TrEMBL
      A0A994J6T8, S4R3U4
      Related
      ENSP00000474751.1, ENST00000604872.6
    3. NM_001349798.2NP_001336727.1  F-box/WD repeat-containing protein 7 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1 and 5 encode the same isoform (1).
      Source sequence(s)
      AC023424, AC080078, BC143944, CA425646
      Consensus CDS
      CCDS3777.1
      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
      Related
      ENSP00000281708.3, ENST00000281708.10
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like
    4. NM_018315.5NP_060785.2  F-box/WD repeat-containing protein 7 isoform 2

      See identical proteins and their annotated locations for NP_060785.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (2) is shorter and has a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC080078, AF411972, BI496455
      Consensus CDS
      CCDS3778.1
      UniProtKB/TrEMBL
      Q53F40
      Related
      ENSP00000377528.4, ENST00000393956.9
      Conserved Domains (3) summary
      cd00200
      Location:294570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:304339
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:201245
      F-box-like
    5. NM_033632.3NP_361014.1  F-box/WD repeat-containing protein 7 isoform 1

      See identical proteins and their annotated locations for NP_361014.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 5 encode the same isoform (1).
      Source sequence(s)
      AC023424, AC080078, AI598129, BC117244
      Consensus CDS
      CCDS3777.1
      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
      Related
      ENSP00000474725.1, ENST00000603548.6
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      152320544..152536092 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011532085.3XP_011530387.1  F-box/WD repeat-containing protein 7 isoform X1

      See identical proteins and their annotated locations for XP_011530387.1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like
    2. XM_047415900.1XP_047271856.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    3. XM_047415902.1XP_047271858.1  F-box/WD repeat-containing protein 7 isoform X2

    4. XM_011532084.3XP_011530386.1  F-box/WD repeat-containing protein 7 isoform X1

      See identical proteins and their annotated locations for XP_011530386.1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like
    5. XM_011532087.3XP_011530389.1  F-box/WD repeat-containing protein 7 isoform X2

      See identical proteins and their annotated locations for XP_011530389.1

      Conserved Domains (3) summary
      cd00200
      Location:346622
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:356391
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:253297
      F-box-like; F-box-like
    6. XM_011532086.3XP_011530388.1  F-box/WD repeat-containing protein 7 isoform X2

      See identical proteins and their annotated locations for XP_011530388.1

      Conserved Domains (3) summary
      cd00200
      Location:346622
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:356391
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:253297
      F-box-like; F-box-like
    7. XM_024454123.2XP_024309891.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like
    8. XM_047415897.1XP_047271853.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    9. XM_024454126.2XP_024309894.1  F-box/WD repeat-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      A0A994J497
      Related
      ENSP00000515368.1, ENST00000703552.1
      Conserved Domains (3) summary
      cd00200
      Location:207483
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:217252
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:114158
      F-box-like
    10. XM_047415898.1XP_047271854.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
      Related
      ENSP00000515369.1, ENST00000703553.1
    11. XM_047415901.1XP_047271857.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    12. XM_047415899.1XP_047271855.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      155643699..155859255 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054350397.1XP_054206372.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    2. XM_054350395.1XP_054206370.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    3. XM_054350401.1XP_054206376.1  F-box/WD repeat-containing protein 7 isoform X2

    4. XM_054350396.1XP_054206371.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    5. XM_054350399.1XP_054206374.1  F-box/WD repeat-containing protein 7 isoform X2

    6. XM_054350400.1XP_054206375.1  F-box/WD repeat-containing protein 7 isoform X2

    7. XM_054350398.1XP_054206373.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    8. XM_054350392.1XP_054206367.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    9. XM_054350403.1XP_054206378.1  F-box/WD repeat-containing protein 7 isoform X3

    10. XM_054350393.1XP_054206368.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    11. XM_054350394.1XP_054206369.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/Swiss-Prot
      B7ZLP9, Q68DR0, Q969H0, Q96A16, Q96LE0, Q96RI2, Q9NUX6
    12. XM_054350402.1XP_054206377.1  F-box/WD repeat-containing protein 7 isoform X2