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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_050651.2Â RefSeqGene
- Range
-
4996..286612
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1183
mRNA and Protein(s)
-
NM_001105515.3 → NP_001098985.1  ATP-binding cassette sub-family C member 4 isoform 2
See identical proteins and their annotated locations for NP_001098985.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks several 3' exons but contains an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a distinct and shorter C-terminus, compared to isoform 1.
- Source sequence(s)
-
AK290317, AL356257, BC041560, BX113883, CN410193
- Consensus CDS
-
CCDS45061.1
- UniProtKB/TrEMBL
-
A8K2Q2
- Related
- ENSP00000487081.1, ENST00000629385.1
- Conserved Domains (3) summary
-
- cd03250
Location:410 → 610
- ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
- COG1132
Location:90 → 633
- MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
- cl00549
Location:96 → 365
- ABC_membrane; ABC transporter transmembrane region
-
NM_001301829.2 → NP_001288758.1  ATP-binding cassette sub-family C member 4 isoform 3
See identical proteins and their annotated locations for NP_001288758.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1.
- Source sequence(s)
-
AL139381, AL157818, AL356257
- Consensus CDS
-
CCDS86356.1
- UniProtKB/Swiss-Prot
-
O15439
- UniProtKB/TrEMBL
-
A8K2Q2
- Related
- ENSP00000494751.1, ENST00000646439.1
- Conserved Domains (5) summary
-
- cd03244
Location:992 → 1211
- ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
- cd03250
Location:410 → 610
- ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
- TIGR01271
Location:11 → 1222
- CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
- pfam00664
Location:677 → 944
- ABC_membrane; ABC transporter transmembrane region
- cl00549
Location:96 → 365
- ABC_membrane; ABC transporter transmembrane region
-
NM_001301830.2 → NP_001288759.1  ATP-binding cassette sub-family C member 4 isoform 4
See identical proteins and their annotated locations for NP_001288759.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region, and also lacks several 3' exons but contains an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (4) has a distinct and shorter C-terminus, compared to isoform 1.
- Source sequence(s)
-
AK290317, AK296247, AL356257, BX113883, CN410193
- Consensus CDS
-
CCDS76643.1
- UniProtKB/TrEMBL
-
A8K2Q2
- Related
- ENSP00000442024.1, ENST00000536256.3
- Conserved Domains (4) summary
-
- cd03250
Location:335 → 535
- ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
- COG1131
Location:353 → 596
- CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
- COG1132
Location:639 → 771
- MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
- cl00549
Location:643 → 770
- ABC_membrane; ABC transporter transmembrane region
-
NM_005845.5 → NP_005836.2  ATP-binding cassette sub-family C member 4 isoform 1
See identical proteins and their annotated locations for NP_005836.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AL139381, AL157818, AL356257
- Consensus CDS
-
CCDS9474.1
- UniProtKB/Swiss-Prot
- A9Z1Z7, B7Z3Q7, O15439, Q8IVZ4, Q8IZN6, Q8NEW8, Q9Y6J2
- Related
- ENSP00000494609.1, ENST00000645237.2
- Conserved Domains (5) summary
-
- cd03244
Location:1039 → 1258
- ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
- cd03250
Location:410 → 610
- ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
- TIGR01271
Location:11 → 1269
- CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
- pfam00664
Location:718 → 991
- ABC_membrane; ABC transporter transmembrane region
- cl00549
Location:96 → 365
- ABC_membrane; ABC transporter transmembrane region
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000013.11Â Reference GRCh38.p14 Primary Assembly
- Range
-
95019835..95301451 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047430034.1 → XP_047285990.1  ATP-binding cassette sub-family C member 4 isoform X1
-
XM_047430035.1 → XP_047285991.1  ATP-binding cassette sub-family C member 4 isoform X2
-
XM_017020320.3 → XP_016875809.1  ATP-binding cassette sub-family C member 4 isoform X3
- UniProtKB/TrEMBL
-
A8K2Q2
Alternate T2T-CHM13v2.0
Genomic
-
NC_060937.1Â Alternate T2T-CHM13v2.0
- Range
-
94223430..94506029 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054373999.1 → XP_054229974.1  ATP-binding cassette sub-family C member 4 isoform X1
-
XM_054374000.1 → XP_054229975.1  ATP-binding cassette sub-family C member 4 isoform X2
-
XM_054374001.1 → XP_054229976.1  ATP-binding cassette sub-family C member 4 isoform X3
- UniProtKB/TrEMBL
-
A8K2Q2