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    Mrps12 mitochondrial ribosomal protein S12 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292758, updated on 10-Jul-2024

    Summary

    Official Symbol
    Mrps12provided by RGD
    Official Full Name
    mitochondrial ribosomal protein S12provided by RGD
    Primary source
    RGD:1306221
    See related
    EnsemblRapid:ENSRNOG00000019949 AllianceGenome:RGD:1306221
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be part of mitochondrial small ribosomal subunit. Predicted to be active in ribosome. Orthologous to human MRPS12 (mitochondrial ribosomal protein S12). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 149.5), Heart (RPKM 139.4) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mrps12 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (93153424..93156422, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (84025896..84028896, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (86920679..86923626, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene MARCKS-related protein-like Neighboring gene uncharacterized LOC134485106 Neighboring gene F-box protein 27 Neighboring gene F-box protein 17 Neighboring gene seryl-tRNA synthetase 2, mitochondrial Neighboring gene NFKB inhibitor beta Neighboring gene coiled-coil glutamate-rich protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein uS12m
    Names
    28S ribosomal protein S12, mitochondrial

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106239.1NP_001099709.1  small ribosomal subunit protein uS12m

      See identical proteins and their annotated locations for NP_001099709.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473979
      UniProtKB/TrEMBL
      A6J9K4, D3ZQX3
      Related
      ENSRNOP00000027029.3, ENSRNOT00000027029.6
      Conserved Domains (1) summary
      cd03368
      Location:32138
      Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      93153424..93156422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228652.5XP_006228714.1  small ribosomal subunit protein uS12m isoform X1

      See identical proteins and their annotated locations for XP_006228714.1

      UniProtKB/TrEMBL
      A6J9K4, D3ZQX3
      Conserved Domains (1) summary
      cd03368
      Location:32138
      Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...
    2. XM_006228651.3XP_006228713.1  small ribosomal subunit protein uS12m isoform X1

      See identical proteins and their annotated locations for XP_006228713.1

      UniProtKB/TrEMBL
      A6J9K4, D3ZQX3
      Conserved Domains (1) summary
      cd03368
      Location:32138
      Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...