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    Cmtm5 CKLF-like MARVEL transmembrane domain containing 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290214, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Cmtm5provided by RGD
    Official Full Name
    CKLF-like MARVEL transmembrane domain containing 5provided by RGD
    Primary source
    RGD:1307045
    See related
    EnsemblRapid:ENSRNOG00000016828 AllianceGenome:RGD:1307045
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cklfsf5
    Summary
    Predicted to act upstream of or within negative regulation of myoblast differentiation. Predicted to be active in membrane. Orthologous to human CMTM5 (CKLF like MARVEL transmembrane domain containing 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 171.5), Heart (RPKM 16.3) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cmtm5 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (32382171..32385288)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (28412624..28415304)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (33600016..33602839)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene embryonal Fyn-associated substrate Neighboring gene interleukin 25 Neighboring gene uncharacterized LOC108352923 Neighboring gene myosin heavy chain 6 Neighboring gene microRNA 3546 Neighboring gene microRNA 208a Neighboring gene uncharacterized LOC120096985 Neighboring gene myosin heavy chain 7 Neighboring gene microRNA 208b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. RNAi screen reveals potentially novel roles of cytokines in myoblast differentiation. Ge Y, et al. PLoS One, 2013. PMID 23844157, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of myoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CKLF-like MARVEL transmembrane domain-containing protein 5
    Names
    chemokine-like factor super family 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106034.2 → NP_001099504.2  CKLF-like MARVEL transmembrane domain-containing protein 5

      See identical proteins and their annotated locations for NP_001099504.2

      Status: VALIDATED

      Source sequence(s)
      AI715540, CX569344, FM029909
      UniProtKB/TrEMBL
      A6KGX8
      Conserved Domains (1) summary
      pfam01284
      Location:29 → 139
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      32382171..32385288
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274121.1 → XP_063130191.1  CKLF-like MARVEL transmembrane domain-containing protein 5 isoform X2

    2. XM_063274122.1 → XP_063130192.1  CKLF-like MARVEL transmembrane domain-containing protein 5 isoform X3

      UniProtKB/TrEMBL
      D3ZQ46
      Related
      ENSRNOP00000022664.7, ENSRNOT00000022664.9

    3. XM_063274120.1 → XP_063130190.1  CKLF-like MARVEL transmembrane domain-containing protein 5 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Chemical Information
    Molecular Biology Databases
    Research Materials