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    Hist1h2an histone cluster 1, H2an [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306970, updated on 14-Nov-2024

    Summary

    Official Symbol
    Hist1h2anprovided by RGD
    Official Full Name
    histone cluster 1, H2anprovided by RGD
    Primary source
    RGD:1309078
    See related
    EnsemblRapid:ENSRNOG00000048264 AllianceGenome:RGD:1309078
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of chromatin. Predicted to be involved in heterochromatin formation. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H2AC4 (H2A clustered histone 4) and H2AC8 (H2A clustered histone 8). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See Hist1h2an in Genome Data Viewer
    Location:
    17p11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (41961533..41963297)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (41534653..41535259)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (43779174..43779775)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene H3 clustered histone 13 Neighboring gene H2A clustered histone 23 Neighboring gene H2B clustered histone like 2 Neighboring gene uncharacterized LOC120097727 Neighboring gene H1.3 linker histone, cluster member

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of nucleosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    histone cluster 1, H2an
    Names
    histone 1, H2an

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107354.1NP_001100824.1  histone cluster 1, H2an

      See identical proteins and their annotated locations for NP_001100824.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474064
      UniProtKB/Swiss-Prot
      Q64598
      UniProtKB/TrEMBL
      A6KLN9, G3V9C0
      Related
      ENSRNOP00000101232.1, ENSRNOT00000134725.1
      Conserved Domains (1) summary
      PTZ00017
      Location:1130
      PTZ00017; histone H2A; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      41961533..41963297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276447.1XP_063132517.1  histone cluster 1, H2an isoform X1

      Related
      ENSRNOP00000109783.1, ENSRNOT00000158781.1