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    PF3D7_1312400 translation initiation factor IF-2, putative [ Plasmodium falciparum 3D7 ]

    Gene ID: 814047, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1312400
    Gene description
    translation initiation factor IF-2, putative
    Locus tag
    PF3D7_1312400
    See related
    PlasmoDB:PF3D7_1312400; VEuPathDB:PF3D7_1312400
    Gene type
    protein coding
    RNA name
    translation initiation factor IF-2, putative
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1312400 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    1
    Sequence:
    Chromosome: 13; NC_004331.3 (521050..524436)

    Chromosome 13 - NC_004331.3Genomic Context describing neighboring genes Neighboring gene conserved protein, unknown function Neighboring gene mitochondrial ribosomal protein S35 precursor, putative Neighboring gene apical ring associated protein 1, putative Neighboring gene conserved Plasmodium protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004331.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Targeting and function of proteins mediating translation initiation in organelles of Plasmodium falciparum. Haider A, et al. Mol Microbiol, 2015 May. PMID 25689481
    2. A Prioritized and Validated Resource of Mitochondrial Proteins in Plasmodium Identifies Unique Biology. van Esveld SL, et al. mSphere, 2021 Oct 27. PMID 34494883, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within translational initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    translation initiation factor IF-2, putative

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004331.3 Reference assembly

      Range
      521050..524436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001349816.1 → XP_001349852.1  translation initiation factor IF-2, putative [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001349852.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024VN94, A0A024W481, A0A0L0CZX8, A0A0L1I7N5, A0A0L7LWG8, Q8IEJ7, W4IB23, W7J777, W7JQL2
      Conserved Domains (3) summary
      pfam11987
      Location:999 → 1099
      IF-2; Translation-initiation factor 2
      cl02787
      Location:476 → 542
      Translation_Factor_II_like; Domain II of Elongation factor Tu (EF-Tu)-like proteins
      cl38936
      Location:214 → 382
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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