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    Ubn2 ubinuclein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312248, updated on 10-Oct-2024

    Summary

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    Official Symbol
    Ubn2provided by RGD
    Official Full Name
    ubinuclein 2provided by RGD
    Primary source
    RGD:1310722
    See related
    EnsemblRapid:ENSRNOG00000005564 AllianceGenome:RGD:1310722
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310722
    Summary
    Predicted to be involved in DNA replication-independent chromatin assembly. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human UBN2 (ubinuclein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 90.8), Thymus (RPKM 78.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ubn2 in Genome Data Viewer
    Location:
    4q23
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (68130497..68218471)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (67165278..67251562)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (66164639..66254297)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene high-mobility group box 1, pseudogene 18 Neighboring gene zinc finger CCCH-type containing, antiviral 1 Neighboring gene high mobility group protein B1 pseudogene Neighboring gene intraflagellar transport 56 Neighboring gene large ribosomal subunit protein uL14-like Neighboring gene uncharacterized LOC134486759

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. Pieragostino D, et al. Mol Biosyst, 2013 Jun. PMID 23580065
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in chromatin organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubinuclein-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134553.1 → NP_001128025.1  ubinuclein-2

      See identical proteins and their annotated locations for NP_001128025.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473959
      UniProtKB/Swiss-Prot
      D4A666
      UniProtKB/TrEMBL
      A0A8I6A379
      Related
      ENSRNOP00000085092.1, ENSRNOT00000096491.2
      Conserved Domains (3) summary
      pfam05722
      Location:1017 → 1132
      Ustilago_mating; Ustilago B locus mating-type protein
      pfam08729
      Location:182 → 231
      HUN; HPC2 and ubinuclein domain
      pfam14075
      Location:442 → 648
      UBN_AB; Ubinuclein conserved middle domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      68130497..68218471
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236311.5 → XP_006236373.1  ubinuclein-2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6A379
      Conserved Domains (3) summary
      pfam05722
      Location:1019 → 1134
      Ustilago_mating; Ustilago B locus mating-type protein
      pfam08729
      Location:182 → 231
      HUN; HPC2 and ubinuclein domain
      pfam14075
      Location:442 → 650
      UBN_AB; Ubinuclein conserved middle domain

    2. XM_063285997.1 → XP_063142067.1  ubinuclein-2 isoform X4

    3. XM_006236306.5 → XP_006236368.1  ubinuclein-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A379, A0A8L2UN89
      Related
      ENSRNOP00000061860.2, ENSRNOT00000064175.3
      Conserved Domains (3) summary
      pfam05722
      Location:1019 → 1134
      Ustilago_mating; Ustilago B locus mating-type protein
      pfam08729
      Location:182 → 231
      HUN; HPC2 and ubinuclein domain
      pfam14075
      Location:442 → 650
      UBN_AB; Ubinuclein conserved middle domain

    4. XM_006236307.5 → XP_006236369.1  ubinuclein-2 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A0V7, A0A8I6A379
      Related
      ENSRNOP00000083893.1, ENSRNOT00000096540.2
      Conserved Domains (3) summary
      pfam05722
      Location:1002 → 1117
      Ustilago_mating; Ustilago B locus mating-type protein
      pfam08729
      Location:182 → 231
      HUN; HPC2 and ubinuclein domain
      pfam14075
      Location:442 → 650
      UBN_AB; Ubinuclein conserved middle domain

    5. XM_006236308.5 → XP_006236370.1  ubinuclein-2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A379
      Conserved Domains (3) summary
      pfam05722
      Location:1000 → 1115
      Ustilago_mating; Ustilago B locus mating-type protein
      pfam08729
      Location:182 → 231
      HUN; HPC2 and ubinuclein domain
      pfam14075
      Location:442 → 648
      UBN_AB; Ubinuclein conserved middle domain

    6. XM_063285998.1 → XP_063142068.1  ubinuclein-2 isoform X6

    7. XM_063285999.1 → XP_063142069.1  ubinuclein-2 isoform X7

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D4A666.1 GenPept UniProtKB/Swiss-Prot:D4A666

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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