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    PLN1 Pln1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853920, updated on 2-Nov-2024

    Summary

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    Official Symbol
    PLN1
    Official Full Name
    Pln1p
    Primary source
    SGD:S000001754
    Locus tag
    YKR046C
    See related
    AllianceGenome:SGD:S000001754; FungiDB:YKR046C; VEuPathDB:YKR046C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PET10
    Summary
    Involved in aerobic respiration. Located in lipid droplet. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See PLN1 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (524223..525074, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Uip5p Neighboring gene uncharacterized protein Neighboring gene histone chaperone NAP1 Neighboring gene putative redox protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast perilipin Pet10p/Pln1p interacts with Erg6p in ergosterol metabolism. Garaiova M, et al. Biochim Biophys Acta Mol Cell Biol Lipids, 2024 Aug. PMID 38734059
    2. Knowledge-based analysis of microarray gene expression data by using support vector machines. Brown MP, et al. Proc Natl Acad Sci U S A, 2000 Jan 4. PMID 10618406, Free PMC Article
    3. Engineering lipid droplet assembly mechanisms for improved triacylglycerol accumulation in Saccharomyces cerevisiae. Teixeira PG, et al. FEMS Yeast Res, 2018 Sep 1. PMID 29897501
    4. Global analysis of protein homomerization in Saccharomyces cerevisiae. Kim Y, et al. Genome Res, 2019 Jan. PMID 30567710, Free PMC Article
    5. Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly. Gao Q, et al. J Cell Biol, 2017 Oct 2. PMID 28801319, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in aerobic respiration IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lipid droplet IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pln1p
    NP_012972.3
    • Perilipin, involved in formation and stability of lipid droplets; expression pattern suggests a role in respiratory growth; computational analysis of large-scale protein-protein interaction data suggests a role in ATP/ADP exchange

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      524223..525074 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179836.3 → NP_012972.3  TPA: Pln1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012972.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXA8, P36139
      UniProtKB/TrEMBL
      A7A007, B3LRC6, B5VMJ4, C7GNL8, C8ZCL1, G2WI75, N1P837
      Conserved Domains (1) summary
      pfam17316
      Location:18 → 267
      PET10; Petite colonies protein 10
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36139.3

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