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    STF2 ATPase-stabilizing factor family protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852891, updated on 9-Jun-2024

    Summary

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    Gene symbol
    STF2
    Gene description
    ATPase-stabilizing factor family protein
    Primary source
    FungiDB:YGR008C
    Locus tag
    YGR008C
    See related
    SGD:S000003240; AllianceGenome:SGD:S000003240; VEuPathDB:YGR008C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in cellular response to desiccation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See STF2 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (508110..508364, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene mRNA splicing protein PRP18 Neighboring gene ethanolamine-phosphate cytidylyltransferase Neighboring gene Sec9p Neighboring gene nicotinamide-nucleotide adenylyltransferase NMA2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High hydrostatic pressure leads to free radicals accumulation in yeast cells triggering oxidative stress. Bravim F, et al. FEMS Yeast Res, 2016 Aug. PMID 27388472
    2. Isolation of a gene for a regulatory 15-kDa subunit of mitochondrial F1F0-ATPase and construction of mutant yeast lacking the protein. Yoshida Y, et al. Eur J Biochem, 1990 Aug 28. PMID 2169416
    3. Binding of an intrinsic ATPase inhibitor to the F(1)FoATPase in phosphorylating conditions of yeast mitochondria. Iwatsuki H, et al. J Biochem, 2000 Oct. PMID 11011137
    4. Simultaneous bindings of ATPase inhibitor and 9K protein to F1F0-ATPase in the presence of 15K protein in yeast mitochondria. Hashimoto T, et al. J Biochem, 1990 Jul. PMID 2172220
    5. Purification and properties of factors in yeast mitochondria stabilizing the F1F0-ATPase-inhibitor complex. Hashimoto T, et al. J Biochem, 1984 Jan. PMID 6200468

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to desiccation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ATPase-stabilizing factor family protein
    NP_011522.1
    • Protein involved in resistance to desiccation stress; Stf2p exhibits antioxidant properties, and its overexpression prevents ROS accumulation and apoptosis; binds to F0 sector of mitochondrial F1F0 ATPase in vitro and may modulate the inhibitory action of Inh1p and Stf1p; protein abundance increases in response to DNA replication stress; STF2 has a paralog, TMA10, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      508110..508364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181137.1 → NP_011522.1  TPA: ATPase-stabilizing factor family protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011522.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUE5, P16965, P89099
      UniProtKB/TrEMBL
      A0A8H4C0D6, A6ZV00, C7GK78, C8Z8Q2, G2WEA1, N1P5N1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P16965.2

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