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    ATG33 Atg33p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851070, updated on 9-Jun-2024

    Summary

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    Gene symbol
    ATG33
    Gene description
    Atg33p
    Primary source
    FungiDB:YLR356W
    Locus tag
    YLR356W
    See related
    SGD:S000004348; AllianceGenome:SGD:S000004348; VEuPathDB:YLR356W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in autophagy of mitochondrion and macroautophagy. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ATG33 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (840321..840914)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate transaldolase TAL1 Neighboring gene ketol-acid reductoisomerase Neighboring gene Rsc2p Neighboring gene uncharacterized protein Neighboring gene adenylosuccinase ADE13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial depolarization in yeast zygotes inhibits clonal expansion of selfish mtDNA. Karavaeva IE, et al. J Cell Sci, 2017 Apr 1. PMID 28193734
    2. Uth1 is a mitochondrial inner membrane protein dispensable for post-log-phase and rapamycin-induced mitophagy. Welter E, et al. FEBS J, 2013 Oct. PMID 23910823
    3. A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast. Wang CW, et al. J Cell Biol, 2014 Aug 4. PMID 25070953, Free PMC Article
    4. Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response. Guerra-Moreno A, et al. J Biol Chem, 2015 Dec 11. PMID 26491016, Free PMC Article
    5. Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics. Díaz-Mejía JJ, et al. Mol Syst Biol, 2018 May 28. PMID 29807908, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in autophagy of mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in macroautophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Atg33p
    NP_013460.1
    • Mitochondrial mitophagy-specific protein; required primarily for mitophagy induced at post-log phase; not required for other types of selective autophagy or macroautophagy; conserved within fungi, but not in higher eukaryotes; ATG33 has a paralog, SCM4, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      840321..840914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182245.1 → NP_013460.1  TPA: Atg33p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013460.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A7A1N4, B3RHM5, C7GRY1, C8ZDW3, D6VYZ4, Q06485
      UniProtKB/TrEMBL
      A0A8H4BZ04, N1P782
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06485.1

    Gene LinkOut

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