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    Tmem123 transmembrane protein 123 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363013, updated on 30-Mar-2024

    Summary

    Official Symbol
    Tmem123provided by RGD
    Official Full Name
    transmembrane protein 123provided by RGD
    Primary source
    RGD:1305625
    See related
    Ensembl:ENSRNOG00000010584 AllianceGenome:RGD:1305625
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305625
    Summary
    Predicted to be involved in oncosis. Predicted to be located in external side of plasma membrane. Predicted to be active in cytoplasmic vesicle. Orthologous to human TMEM123 (transmembrane protein 123). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 999.6), Spleen (RPKM 651.5) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    8q11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (13206907..13237069)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (4922077..4952228)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (5967373..5997387)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102556477 Neighboring gene galectin-8 pseudogene Neighboring gene matrix metallopeptidase 7 Neighboring gene baculoviral IAP repeat-containing 2 Neighboring gene baculoviral IAP repeat-containing 3 Neighboring gene RNA guanine-7 methyltransferase activating subunit, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014205.2NP_001014227.1  porimin precursor

      See identical proteins and their annotated locations for NP_001014227.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q5HZB0
      UniProtKB/TrEMBL
      A0A8I6A004
      Related
      ENSRNOP00000014065.6, ENSRNOT00000014065.8
      Conserved Domains (1) summary
      pfam05283
      Location:94174
      MGC-24; Multi-glycosylated core protein 24 (MGC-24), sialomucin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      13206907..13237069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265682.1XP_063121752.1  porimin isoform X1