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    JID1 Jid1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856174, updated on 17-May-2024

    Summary

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    Gene symbol
    JID1
    Gene description
    Jid1p
    Primary source
    FungiDB:YPR061C
    Locus tag
    YPR061C
    See related
    SGD:S000006265; AllianceGenome:SGD:S000006265
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrion. Is integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (675977..676882, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene organic acid transporter Neighboring gene chorismate mutase ARO7 Neighboring gene cytosine deaminase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Jid1 is a J-protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation. Bursać D, et al. FEBS Lett, 2009 Sep 3. PMID 19682992
    2. Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Kushner DB, et al. Proc Natl Acad Sci U S A, 2003 Dec 23. PMID 14671320, Free PMC Article
    3. Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD. Taxis C, et al. J Biol Chem, 2003 Sep 19. PMID 12847107
    4. Assessing systems properties of yeast mitochondria through an interaction map of the organelle. Perocchi F, et al. PLoS Genet, 2006 Oct 20. PMID 17054397, Free PMC Article
    5. Identification of a protein mediating respiratory supercomplex stability. Chen YC, et al. Cell Metab, 2012 Mar 7. PMID 22405070, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that Jid1 is confined within the mitochondrial matrix and is unavailable to participate directly in the regulation of ERAD.
      Title: Jid1 is a J-protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Jid1p
    NP_015386.1
    • Probable Hsp40p co-chaperone; has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      675977..676882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184158.1 → NP_015386.1  TPA: Jid1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015386.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W466, Q12350
      UniProtKB/TrEMBL
      A0A8H4F6W8, A6ZWU9, B3LLB5, B5VTL2, C7GY47, G2WPN4, N1NVK2
      Conserved Domains (1) summary
      cl02542
      Location:84 → 147
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12350.1

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