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    DAN1 Dan1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853615, updated on 23-Nov-2023

    Summary

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    Gene symbol
    DAN1
    Gene description
    Dan1p
    Primary source
    SGD:S000003911
    Locus tag
    YJR150C
    See related
    AllianceGenome:SGD:S000003911
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CCW13
    Summary
    Predicted to be a structural constituent of cell wall. Involved in sterol transport. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (708811..709707, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene branched-chain-amino-acid transaminase BAT2 Neighboring gene putative nitronate monooxygenase Neighboring gene Dan4p Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Engineering promoter regulation. Nevoigt E, et al. Biotechnol Bioeng, 2007 Feb 15. PMID 16964624
    2. SUT1-promoted sterol uptake involves the ABC transporter Aus1 and the mannoprotein Dan1 whose synergistic action is sufficient for this process. Alimardani P, et al. Biochem J, 2004 Jul 1. PMID 15035656, Free PMC Article
    3. Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeast. Wilcox LJ, et al. J Biol Chem, 2002 Sep 6. PMID 12077145
    4. Induction of DAN/TIR yeast cell wall mannoprotein genes in response to high hydrostatic pressure and low temperature. Abe F. FEBS Lett, 2007 Oct 16. PMID 17910955
    5. SUT1p interaction with Cyc8p(Ssn6p) relieves hypoxic genes from Cyc8p-Tup1p repression in Saccharomyces cerevisiae. Régnacq M, et al. Mol Microbiol, 2001 Jun. PMID 11401714

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables structural constituent of cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sterol transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Dan1p
    NP_012684.4
    • Cell wall mannoprotein; has similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      708811..709707 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181808.4 → NP_012684.4  TPA: Dan1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012684.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWW8, O94102, P47178
      UniProtKB/TrEMBL
      A0A8H4BZ06, A6ZQA6, B3LQM9, B5VLT7, G2WHF2, N1P1V2
      Conserved Domains (1) summary
      pfam00660
      Location:25 → 117
      SRP1_TIP1; Seripauperin and TIP1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47178.2

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