Primary myelofibrosis
- Synonyms
- Myelofibrosis, somatic; Suspected idiopathic myelofibrosis
- Modes of inheritance
- Not genetically inherited (Orphanet)
Summary
Available tests
Check Related conditions for additional relevant tests.
Clinical tests (111 available)
Cytogenetics Tests
Genes See tests for all associated and related genes
Also known as: CALR1, CRT, HEL-S-99n, RO, SSA, cC1qR, CALR
Summary: calreticulinAlso known as: JTK10, JAK2
Summary: Janus kinase 2Also known as: C-MPL, CD110, MPLV, THCYT2, THPOR, TPOR, MPL
Summary: MPL proto-oncogene, thrombopoietin receptorAlso known as: IDDM20, LNK, SH2B3
Summary: SH2B adaptor protein 3
Clinical features
Help- Abnormality of blood and blood-forming tissues
- Extramedullary hematopoiesis
Extramedullary hematopoiesis
- MedGen UID: 392862
- Concept ID: C2613439
- Finding: Disease or Syndrome
Abnormality of blood and blood-forming tissues
- Myelofibrosis
Myelofibrosis
- MedGen UID: 10146
- Concept ID: C0026987
- Finding: Neoplastic Process
Abnormality of blood and blood-forming tissues
- Extramedullary hematopoiesis
- Abnormality of metabolism/homeostasis
- Fever
Fever
- MedGen UID: 5169
- Concept ID: C0015967
- Finding: Sign or Symptom
Abnormality of metabolism/homeostasis
- Fever
- Abnormality of the digestive system
- Hepatomegaly
Hepatomegaly
- MedGen UID: 42428
- Concept ID: C0019209
- Finding: Finding
Abnormality of the digestive system
- Hepatomegaly
- Abnormality of the immune system
- Hemophagocytosis
Hemophagocytosis
- MedGen UID: 163750
- Concept ID: C0876991
- Finding: Disease or Syndrome
Abnormality of the immune system
- Splenomegaly
Splenomegaly
- MedGen UID: 52469
- Concept ID: C0038002
- Finding: Finding
Abnormality of the immune system
- Hemophagocytosis
- Abnormality of the integument
- Neoplasm
- Myeloproliferative disorder
Myeloproliferative disorder
- MedGen UID: 10147
- Concept ID: C0027022
- Finding: Neoplastic Process
Neoplasm
- Myeloproliferative disorder
- NCCN, 2023NCCN Clinical Practice Guidelines in Oncology (NCCN GuidelinesĀ®), Myeloproliferative Neoplasms, 2023
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