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GTR Home > Conditions/Phenotypes > Severe combined immunodeficiency disease


A type of primary immune deficiency that is characterized by a more severe defect in both the T- and B-lymphocyte systems. [from HPO]

Genes See tests for all associated and related genes

  • Related genesHelp

Practice guidelines

  • ACMG ACT, 2012
    American College of Medical Genetics and Genomics, Newborn Screening ACT Sheet, Severe Combined Immunodeficiency (SCID) and Conditions Associated with T Cell Lymphopenia, 2012

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