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GTR Home > Conditions/Phenotypes > Glomerulopathy with fibronectin deposits 2

Glomerulopathy with fibronectin deposits 2

Synonyms
Glomerular nephritis familial with fibronectin deposits

Summary

Glomerulopathy with fibronectin deposits is a genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life. Pathologic examination shows enlarged glomeruli with mesangial and subendothelial fibrillary deposits that show strong immunoreactivity to fibronectin (Castelletti et al., 2008). For a discussion of genetic heterogeneity of GFND, see 137950. [from OMIM]

Available tests

21 tests are in the database for this condition.

Clinical tests (21 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, SMDCF, FN1
    Summary: fibronectin 1

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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