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GTR Home > Conditions/Phenotypes > Delayed puberty, self-limited

Delayed puberty, self-limited

Synonyms
CONSTITUTIONAL DELAY OF PUBERTY

Summary

Self-limited delayed puberty (DPSL) is characterized by delayed development of Tanner stage G2 accompanied by low serum gonadotropins. Affected individuals experience spontaneous attainment of Tanner stage G4 by 18 years of age, with normalization of gonadotropins, which excludes a diagnosis of hypogonadotropic hypogonadism (see 147950) (Mancini et al., 2020). [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: BNMD17, DPSL, GPR48, LGR4
    Summary: leucine rich repeat containing G protein-coupled receptor 4

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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