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GTR Home > Conditions/Phenotypes > Frontotemporal dementia and/or amyotrophic lateral sclerosis 4

Frontotemporal dementia and/or amyotrophic lateral sclerosis 4

Synonyms
FTDALS4

Summary

Frontotemporal dementia and/or amyotrophic lateral sclerosis-4 is an autosomal dominant neurodegenerative disorder characterized by adult or late adult onset of cognitive impairment, behavioral abnormalities, and speech apraxia and/or upper and lower motor neuron signs. The phenotype is highly variable (summary by Freischmidt et al., 2015). For a discussion of genetic heterogeneity of FTDALS, see FTDALS1 (105550). [from OMIM]

Available tests

20 tests are in the database for this condition.

Clinical tests (20 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: AIARV, FTDALS4, IIAE8, NAK, T2K, TBK1
    Summary: TANK binding kinase 1

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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