U.S. flag

An official website of the United States government

GTR Home > Conditions/Phenotypes > Restrictive dermopathy 1


A restrictive dermopathy that has material basis in homozygous or compound heterozygous mutation in the ZMPSTE24 gene on chromosome 1p34. [from MONDO]

Genes See tests for all associated and related genes

  • Also known as: FACE-1, FACE1, HGPS, PRO1, RSDM1, STE24, Ste24p, ZMPSTE24
    Summary: zinc metallopeptidase STE24

Clinical features


Show allHide all

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.