STAMBP STAM binding protein
Gene ID: 10617, updated on 2-Nov-2024Gene type: protein coding
Also known as: AMSH; MICCAP
Summary
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Associated conditions
| Description | Tests |
|---|---|
| Microcephaly-capillary malformation syndrome | not available |
Genomic context
- Location:
- 2p13.1
- Sequence:
- Chromosome: 2; NC_000002.12 (73828961..73873656)
- Total number of exons:
- 16
Variation
| Resource | Links for this gene |
|---|---|
| SNP | Variation Viewer for STAMBP variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
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