ADRB1 adrenoceptor beta 1
Gene ID: 153, updated on 2-Nov-2024Gene type: protein coding
Also known as: RHR; B1AR; FNSS2; ADRB1R; BETA1AR
- See all available tests in GTR for this gene
- Go to complete Gene record for ADRB1
- Go to Variation Viewer for ADRB1 variants
Summary
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. GeneReviews: Not available | |
| Genome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation. GeneReviews: Not available | |
| New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. GeneReviews: Not available | |
| Resting heart rate | not available |
| SHORT SLEEP, FAMILIAL NATURAL, 2 | not available |
Genomic context
- Location:
- 10q25.3
- Sequence:
- Chromosome: 10; NC_000010.11 (114043866..114046904)
- Total number of exons:
- 1
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ADRB1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ADRB1 database
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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