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DNA2 DNA replication helicase/nuclease 2

Gene ID: 1763, updated on 5-Mar-2024
Gene type: protein coding
Also known as: DNA2L; hDNA2


This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Genomic context

Chromosome: 10; NC_000010.11 (68414064..68472521, complement)
Total number of exons:


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