KCNK18 potassium two pore domain channel subfamily K member 18
Gene ID: 338567, updated on 2-Nov-2024Gene type: protein coding
Also known as: TRIK; MGR13; TRESK; TRESK2; K2p18.1; TRESK-2
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- Go to complete Gene record for KCNK18
- Go to Variation Viewer for KCNK18 variants
Summary
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains and the encoded protein functions as an outward rectifying potassium channel. A mutation in this gene has been found to be associated with migraine with aura.[provided by RefSeq, Jan 2011]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Migraine, with or without aura, susceptibility to, 13 | not available |
Genomic context
- Location:
- 10q25.3
- Sequence:
- Chromosome: 10; NC_000010.11 (117197489..117210299)
- Total number of exons:
- 3
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for KCNK18 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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