MEIS2 Meis homeobox 2
Gene ID: 4212, updated on 2-Nov-2024Gene type: protein coding
Also known as: MRG1; CPCMR; HsT18361
- See all available tests in GTR for this gene
- Go to complete Gene record for MEIS2
- Go to Variation Viewer for MEIS2 variants
Summary
This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Cardiac malformation, cleft lip/palate, microcephaly, and digital anomalies | See labs |
| Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. GeneReviews: Not available | |
| Genome-wide association study and meta-analysis of intraocular pressure. GeneReviews: Not available | |
| Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. GeneReviews: Not available |
Copy number response
| Description |
|---|
| Copy number response Haploinsufficency Sufficient evidence for dosage pathogenicity (Last evaluated 2021-09-14) ClinGen Genome Curation PagePubMedTriplosensitivity No evidence available (Last evaluated 2021-09-14) ClinGen Genome Curation Page |
Genomic context
- Location:
- 15q14
- Sequence:
- Chromosome: 15; NC_000015.10 (36889204..37101311, complement)
- Total number of exons:
- 15
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for MEIS2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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