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MLLT10 MLLT10 histone lysine methyltransferase DOT1L cofactor

Gene ID: 8028, updated on 5-Mar-2024
Gene type: protein coding
Also known as: AF10


This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Associated conditions

See all available tests in GTR for this gene

Acute myeloid leukemiaSee labs
Common variation at 10p12.31 near MLLT10 influences meningioma risk.
GeneReviews: Not available
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
GeneReviews: Not available
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
GeneReviews: Not available

Genomic context

Chromosome: 10; NC_000010.11 (21533756..21743630)
Total number of exons:


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