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GTR Home > Tests > ARVCNext™

Indication

This is a clinical test intended for Help: Diagnosis, Pre-symptomatic

Clinical summary

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Imported from GeneReviews Overview

Arrhythmogenic right ventricular cardiomyopathy (ARVC) – previously referred to as arrhythmogenic right ventricular dysplasia (ARVD) – is characterized by progressive fibrofatty replacement of the myocardium that predisposes to ventricular tachycardia and sudden death in young individuals and athletes. It primarily affects the right ventricle, and it may also involve the left ventricle. The presentation of disease is highly variable even within families, and some affected individuals may not meet established clinical criteria. The mean age at diagnosis is 31 years (±13; range: 4-64 years).

Clinical features

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Imported from Human Phenotype Ontology (HPO)

  • Dyspnea
  • Palpitations
  • Syncope
  • Sudden cardiac death
  • Ventricular arrhythmia
  • Wooly hair
  • Right ventricular cardiomyopathy
  • Palmoplantar keratoderma
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Inheritance pattern

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Autosomal dominant inheritance

Conditions tested

Target population

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Not provided

Clinical validity

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Clinical validity depends on specific clinical and family history.

Citations

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Clinical utility

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Not provided

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