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GTR Home > Tests > Guardant360 TissueNext

Overview

Test name

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Guardant360 TissueNext

Purpose of the test

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This is a clinical test intended for Help: Therapeutic management

Condition

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Click Indication tab for more information.

How to order

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Licensed physician contacts Guardant Health client services for ordering information.
Order URL Help: https://www.guardanthealth.com/medical-professionals

Specimen source

Paraffin block

Methodology

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Molecular Genetics
MMethylation analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Other
  • None/not applicable
IMicrosatellite instability testing (MSI)
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Other
  • None/not applicable
ESequence analysis of select exons
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Other
  • None/not applicable
TTargeted variant analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Other
  • None/not applicable

Summary of what is tested

Click Methodology tab for more information.

Clinical utility

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Guidance for management

Clinical validity

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Matched tumor samples obtained for multiple cancer types in which variants were verified by external laboratories were used in clinical validity studies.

Citations

Not provided

Testing strategy

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TissueNext testing algorithm is based on FDA-approved therapies and professional guidelines. When TissueNext is ordered and no actionable biomarker is identified with Guardant360 CDx, Guardant360 TissueNext will be run and reported when originally requested by the ordering provider. 000 Licensed physician contacts Guardant Health client services for ordering information.

Test services

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  • Tissue testing for somatic cancer gene variants

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.