Pain PGx Panel

GTR Test IDHelpEach Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version number is assigned.: GTR000604048.1
Last updated: 2023-01-24
Test version history
- 604048.1, last updated: 2023-01-24

Clinical testHelpIn the U.S., clinical tests must be performed under CLIA certification. When a lab uses the same methods for a test in both clinical and research settings, the test appears as two separate GTR records. for Methadone response
Offered by Dynamic DNA Laboratories, LLC

Overview

Test order codeHelp: Pain-PGx

Pain PGx Panel (Pain)

This is a clinical test intended for HelpPurposes or indications for the test. Lab-provided.: Drug Response

Click Indication tab for more information.

Contact laboratory to receive requisition form. If this is the first time ordering, a new account setup form is also required. Kits for buccal cell collection are provided along with pre-paid and pre-labeled return mailers.
Order URL HelpLink to the laboratory webpage with information about how to order this test. Please note that clicking on this link will open a new tab in your internet browser.: https://dynamicdnalabs.com/pages/providers

Specimen source

Buccal swab

Molecular Genetics
DDeletion/duplication analysis RT-qPCR Other
TTargeted variant analysis Microarray Illumina iScan

Summary of what is tested

Click Methodology tab for more information.

Guidance for selecting a drug therapy and/or dose

Citations

https://www.fda.gov/drugs/science-and-research-drugs/table-pharmacogenomic-biomarkers-drug-labeling

All drugs are metabolized to some extent in the human body. Nearly all of the enzymes and transporters involved in drug metabolism are known to contain genetic polymorphisms across the human population. Some of these polymorphisms are known to contribute to altered function and subsequent altered drug metabolism. Therefore, determination of known polymorphisms contained in each drug-metabolizing enzyme can be predictive of enzyme activity and overall drug metabolism. This allows for the adjustment of dose or selection of an alternate medication if an individual patient’s phenotype requires. Pharmacogenomic testing has been proven to be a valuable tool for patients undergoing a wide range of drug therapies.

Citations

DOI: 10.1016/bs.apha.2018.04.004
DOI: 10.1186/gm499

Order test before prescribing high risk medication. Only final reports are issued. 000 Contact laboratory to receive requisition form. If this is the first time ordering, a new account setup form is also required. Kits for buccal cell collection are provided along with pre-paid and pre-labeled return mailers.

Clinical Testing/Confirmation of Mutations Identified Previously, comments
Pharmacogenomic Testing

Reviews

Clinical resources

Practice guidelines

DailyMed Drug Label, 2021
DailyMed Drug Label, METHADONE HYDROCHLORIDE, 2021
DailyMed Drug Label, 2007
DailyMed Drug Label, methadone, 2007

Consumer resources

MedlinePlus

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.

Pain PGx Panel

Overview

Test name

Purpose of the test

Condition

How to order

Specimen source

Methodology

Summary of what is tested

Clinical utility

Guidance for selecting a drug therapy and/or dose

Clinical validity

Testing strategy

Test services

Reviews

Clinical resources

Practice guidelines

Consumer resources