GenepoweRx_Cardiac Care
Clinical Genetic Test
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GTR Test Accession: Help GTR000607941.1
INHERITED DISEASECARDIOVASCULARSYNDROMIC DISEASE ... View more
Last updated in GTR: 2023-07-20
Last annual review date for the lab: 2023-05-19 LinkOut
At a Glance
Pre-symptomatic; Therapeutic management; Risk Assessment; ...
Coronary artery disease, autosomal dominant, 1; Atrial fibrillation, familial, 1; Atrial fibrillation, familial, 10; ...
ABCA1 (9q31.1), ABCC9 (12p12.1), ACTC1 (15q14), ACTN2 (1q43), AKAP9 (7q21.2), ...
Molecular Genetics - Deletion/duplication analysis: Next-Generation (NGS)/Massively parallel sequencing (MPS); ...
Individuals with clinical symptoms consistent with Coronary artery disease risk, …
Not provided
Not provided
Ordering Information
Offered by: Help
Test Order Code: Help
KHMDCVGPCAD1
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Conditions Help
Total conditions: 63
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 102
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 4
Method Category Help
Test method Help
Instrument *
Deletion/duplication analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Detection of homozygosity
Oligonucleotide hybridization-based DNA sequencing
Mutation scanning of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Targeted variant analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
* Instrument: Not provided
Clinical Information
Test purpose: Help
Pre-symptomatic; Therapeutic management; Risk Assessment; Mutation Confirmation; Prognostic; Diagnosis; Screening
Target population: Help
Individuals with clinical symptoms consistent with Coronary artery disease risk, Hypertrophic cardiomyopathy risk, Arrhythmia, Brugada Syndrome, Atrial fibrillation, Long QT syndrome, Ventricular Arrhythmia, Cardiac Channelopathies, Familial Hypercholesterolemia or individuals with distorted lifestyle factors
Recommended fields not provided:
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
Repeatability and reproducibility of alterations associated with this test were evaluated. The results confirmed that the test is robust regarding repeatability and reproducibility of variant calling. Across all samples, the pre-sequencing process failure was ≤ 1%. All variants from all samples were consistent by 99.9%.
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
No
Recommended fields not provided:
Regulatory Approval
FDA Review: Help
Not provided
Additional Information

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