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Injection site disorder

MedGen UID:
101800
Concept ID:
C0151735
Pathologic Function
Synonyms: Injection Site Adverse Event; Injection Site Event; Injection Site Events; Injection Site Reaction; Injection Site Reactions
SNOMED CT: Injection site disorder (95376002)

Definition

An intense reaction (usually immunologic) developing at the site of injection [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInjection site disorder

Professional guidelines

PubMed

Kim JT, Park JY, Lee HJ, Cheon YJ
J Educ Eval Health Prof 2020;17:21. Epub 2020 Jul 16 doi: 10.3352/jeehp.2020.17.21. PMID: 32668826Free PMC Article
Nawrocki S, Cha J
J Am Acad Dermatol 2020 Apr;82(4):969-979. Epub 2019 Dec 4 doi: 10.1016/j.jaad.2019.11.042. PMID: 31811879
Plachouri KM, Georgiou S
J Cosmet Dermatol 2019 Dec;18(6):1601-1605. Epub 2019 Aug 24 doi: 10.1111/jocd.13115. PMID: 31444843

Recent clinical studies

Etiology

Niemann N, Billnitzer A, Jankovic J
Parkinsonism Relat Disord 2021 Jan;82:61-76. Epub 2020 Nov 20 doi: 10.1016/j.parkreldis.2020.11.017. PMID: 33248395
Sandborn WJ, Baert F, Danese S, Krznarić Ž, Kobayashi T, Yao X, Chen J, Rosario M, Bhatia S, Kisfalvi K, D'Haens G, Vermeire S
Gastroenterology 2020 Feb;158(3):562-572.e12. Epub 2019 Aug 28 doi: 10.1053/j.gastro.2019.08.027. PMID: 31470005
Plachouri KM, Georgiou S
J Cosmet Dermatol 2019 Dec;18(6):1601-1605. Epub 2019 Aug 24 doi: 10.1111/jocd.13115. PMID: 31444843
Detke HC, Goadsby PJ, Wang S, Friedman DI, Selzler KJ, Aurora SK
Neurology 2018 Dec 11;91(24):e2211-e2221. Epub 2018 Nov 16 doi: 10.1212/WNL.0000000000006640. PMID: 30446596Free PMC Article
Mahlangu J, Oldenburg J, Paz-Priel I, Negrier C, Niggli M, Mancuso ME, Schmitt C, Jiménez-Yuste V, Kempton C, Dhalluin C, Callaghan MU, Bujan W, Shima M, Adamkewicz JI, Asikanius E, Levy GG, Kruse-Jarres R
N Engl J Med 2018 Aug 30;379(9):811-822. doi: 10.1056/NEJMoa1803550. PMID: 30157389

Diagnosis

Sharifian-Dorche M, Bahmanyar M, Sharifian-Dorche A, Mohammadi P, Nomovi M, Mowla A
J Neurol Sci 2021 Sep 15;428:117607. Epub 2021 Aug 3 doi: 10.1016/j.jns.2021.117607. PMID: 34365148Free PMC Article
Niemann N, Billnitzer A, Jankovic J
Parkinsonism Relat Disord 2021 Jan;82:61-76. Epub 2020 Nov 20 doi: 10.1016/j.parkreldis.2020.11.017. PMID: 33248395
Kim JT, Park JY, Lee HJ, Cheon YJ
J Educ Eval Health Prof 2020;17:21. Epub 2020 Jul 16 doi: 10.3352/jeehp.2020.17.21. PMID: 32668826Free PMC Article
Simpson EL, Paller AS, Siegfried EC, Boguniewicz M, Sher L, Gooderham MJ, Beck LA, Guttman-Yassky E, Pariser D, Blauvelt A, Weisman J, Lockshin B, Hultsch T, Zhang Q, Kamal MA, Davis JD, Akinlade B, Staudinger H, Hamilton JD, Graham NMH, Pirozzi G, Gadkari A, Eckert L, Stahl N, Yancopoulos GD, Ruddy M, Bansal A
JAMA Dermatol 2020 Jan 1;156(1):44-56. doi: 10.1001/jamadermatol.2019.3336. PMID: 31693077Free PMC Article
Thomaidou E, Ramot Y
Dermatol Ther 2019 Mar;32(2):e12817. Epub 2019 Jan 29 doi: 10.1111/dth.12817. PMID: 30637967

Therapy

Park K, Haura EB, Leighl NB, Mitchell P, Shu CA, Girard N, Viteri S, Han JY, Kim SW, Lee CK, Sabari JK, Spira AI, Yang TY, Kim DW, Lee KH, Sanborn RE, Trigo J, Goto K, Lee JS, Yang JC, Govindan R, Bauml JM, Garrido P, Krebs MG, Reckamp KL, Xie J, Curtin JC, Haddish-Berhane N, Roshak A, Millington D, Lorenzini P, Thayu M, Knoblauch RE, Cho BC
J Clin Oncol 2021 Oct 20;39(30):3391-3402. Epub 2021 Aug 2 doi: 10.1200/JCO.21.00662. PMID: 34339292Free PMC Article
Al Khames Aga QA, Alkhaffaf WH, Hatem TH, Nassir KF, Batineh Y, Dahham AT, Shaban D, Al Khames Aga LA, Agha MYR, Traqchi M
J Med Virol 2021 Dec;93(12):6588-6594. Epub 2021 Jul 28 doi: 10.1002/jmv.27214. PMID: 34270094Free PMC Article
Nawrocki S, Cha J
J Am Acad Dermatol 2020 Apr;82(4):969-979. Epub 2019 Dec 4 doi: 10.1016/j.jaad.2019.11.042. PMID: 31811879
Usach I, Martinez R, Festini T, Peris JE
Adv Ther 2019 Nov;36(11):2986-2996. Epub 2019 Oct 5 doi: 10.1007/s12325-019-01101-6. PMID: 31587143Free PMC Article
Plachouri KM, Georgiou S
J Cosmet Dermatol 2019 Dec;18(6):1601-1605. Epub 2019 Aug 24 doi: 10.1111/jocd.13115. PMID: 31444843

Prognosis

Al Khames Aga QA, Alkhaffaf WH, Hatem TH, Nassir KF, Batineh Y, Dahham AT, Shaban D, Al Khames Aga LA, Agha MYR, Traqchi M
J Med Virol 2021 Dec;93(12):6588-6594. Epub 2021 Jul 28 doi: 10.1002/jmv.27214. PMID: 34270094Free PMC Article
Clément K, van den Akker E, Argente J, Bahm A, Chung WK, Connors H, De Waele K, Farooqi IS, Gonneau-Lejeune J, Gordon G, Kohlsdorf K, Poitou C, Puder L, Swain J, Stewart M, Yuan G, Wabitsch M, Kühnen P; Setmelanotide POMC and LEPR Phase 3 Trial Investigators
Lancet Diabetes Endocrinol 2020 Dec;8(12):960-970. Epub 2020 Oct 30 doi: 10.1016/S2213-8587(20)30364-8. PMID: 33137293
Kassir M, Gupta M, Galadari H, Kroumpouzos G, Katsambas A, Lotti T, Vojvodic A, Grabbe S, Juchems E, Goldust M
J Cosmet Dermatol 2020 Mar;19(3):570-573. Epub 2019 Dec 30 doi: 10.1111/jocd.13266. PMID: 31889407
Weiss RD, Rao V
Drug Alcohol Depend 2017 Apr 1;173 Suppl 1(Suppl 1):S48-S54. doi: 10.1016/j.drugalcdep.2016.12.001. PMID: 28363320Free PMC Article
Jia Z, Lu H, Yang X, Jin X, Wu R, Zhao J, Chen L, Qi Z
Aesthetic Plast Surg 2016 Oct;40(5):769-77. Epub 2016 Aug 5 doi: 10.1007/s00266-016-0682-1. PMID: 27495260

Clinical prediction guides

Schmoele-Thoma B, Zareba AM, Jiang Q, Maddur MS, Danaf R, Mann A, Eze K, Fok-Seang J, Kabir G, Catchpole A, Scott DA, Gurtman AC, Jansen KU, Gruber WC, Dormitzer PR, Swanson KA
N Engl J Med 2022 Jun 23;386(25):2377-2386. doi: 10.1056/NEJMoa2116154. PMID: 35731653
Haller JT, Bonnin S, Radosevich J
Epilepsia 2021 Aug;62(8):1865-1870. Epub 2021 Jun 24 doi: 10.1111/epi.16961. PMID: 34164804
McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Blumenthal KG, Fox LP, Freeman EE
J Am Acad Dermatol 2021 Jul;85(1):46-55. Epub 2021 Apr 7 doi: 10.1016/j.jaad.2021.03.092. PMID: 33838206Free PMC Article
Kassir M, Gupta M, Galadari H, Kroumpouzos G, Katsambas A, Lotti T, Vojvodic A, Grabbe S, Juchems E, Goldust M
J Cosmet Dermatol 2020 Mar;19(3):570-573. Epub 2019 Dec 30 doi: 10.1111/jocd.13266. PMID: 31889407
Sandborn WJ, Baert F, Danese S, Krznarić Ž, Kobayashi T, Yao X, Chen J, Rosario M, Bhatia S, Kisfalvi K, D'Haens G, Vermeire S
Gastroenterology 2020 Feb;158(3):562-572.e12. Epub 2019 Aug 28 doi: 10.1053/j.gastro.2019.08.027. PMID: 31470005

Recent systematic reviews

Seirafianpour F, Pourriyahi H, Gholizadeh Mesgarha M, Pour Mohammad A, Shaka Z, Goodarzi A
Dermatol Ther 2022 Jun;35(6):e15461. Epub 2022 Apr 11 doi: 10.1111/dth.15461. PMID: 35316551Free PMC Article
Sharif N, Alzahrani KJ, Ahmed SN, Dey SK
Front Immunol 2021;12:714170. Epub 2021 Oct 11 doi: 10.3389/fimmu.2021.714170. PMID: 34707602Free PMC Article
Sharifian-Dorche M, Bahmanyar M, Sharifian-Dorche A, Mohammadi P, Nomovi M, Mowla A
J Neurol Sci 2021 Sep 15;428:117607. Epub 2021 Aug 3 doi: 10.1016/j.jns.2021.117607. PMID: 34365148Free PMC Article
Xing K, Tu XY, Liu M, Liang ZW, Chen JN, Li JJ, Jiang LG, Xing FQ, Jiang Y
Zhongguo Dang Dai Er Ke Za Zhi 2021 Mar;23(3):221-228. doi: 10.7499/j.issn.1008-8830.2101133. PMID: 33691913Free PMC Article
Patel P, Leeder JS, Piquette-Miller M, Dupuis LL
Br J Clin Pharmacol 2017 Oct;83(10):2148-2162. Epub 2017 Jun 10 doi: 10.1111/bcp.13322. PMID: 28470980Free PMC Article

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