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Nodular sclerosis classical Hodgkin lymphoma

MedGen UID:
101830
Concept ID:
C0152268
Neoplastic Process
Synonym: Classic Hodgkin lymphoma, nodular sclerosis type
SNOMED CT: Hodgkin's disease, nodular sclerosis (118608000); Hodgkin's disease, nodular sclerosis (clinical) (118608000); Classical Hodgkin lymphoma, nodular sclerosis (52248008); Hodgkin lymphoma, nodular sclerosis (52248008); Hodgkin disease, nodular sclerosis (118608000)
 
Monarch Initiative: MONDO:0004665
Orphanet: ORPHA98843

Definition

A subtype of classic Hodgkin lymphoma characterized by collagen bands that surround at least one nodule, and Hodgkin and Reed-Sternberg cells with lacunar type morphology. (WHO, 2008) [from NCI]

Professional guidelines

PubMed

Ansell SM
Am J Hematol 2022 Nov;97(11):1478-1488. Epub 2022 Sep 19 doi: 10.1002/ajh.26717. PMID: 36215668
Ansell SM
Am J Hematol 2020 Aug;95(8):978-989. Epub 2020 Jun 8 doi: 10.1002/ajh.25856. PMID: 32384177
Ansell SM
Mayo Clin Proc 2015 Nov;90(11):1574-83. doi: 10.1016/j.mayocp.2015.07.005. PMID: 26541251

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Pediatric Hodgkin Lymphoma, 2024

Recent clinical studies

Etiology

Swart L, Novitzky N, Mohamed Z, Opie J
Ann Hematol 2019 Feb;98(2):381-389. Epub 2018 Nov 5 doi: 10.1007/s00277-018-3533-0. PMID: 30397846
Al-Antary E, Jesudas R, George A, Poulik J, Savaşan S
J Pediatr Hematol Oncol 2019 Apr;41(3):e167-e170. doi: 10.1097/MPH.0000000000001245. PMID: 30028823
Martin P, Martínez-Velasquez J, Coronado MJ, Krsnik I, Provencio M, Navarro B, Moraru M, Bellas C, Vilches C, Gomez-Lozano N
Leuk Lymphoma 2017 Feb;58(2):438-444. Epub 2016 Jun 7 doi: 10.1080/10428194.2016.1190972. PMID: 27267403
Rasmussen SL, Thomsen C
Diagn Pathol 2015 Apr 16;10:25. doi: 10.1186/s13000-015-0271-7. PMID: 25890312Free PMC Article

Diagnosis

Swart L, Novitzky N, Mohamed Z, Opie J
Ann Hematol 2019 Feb;98(2):381-389. Epub 2018 Nov 5 doi: 10.1007/s00277-018-3533-0. PMID: 30397846
Al-Antary E, Jesudas R, George A, Poulik J, Savaşan S
J Pediatr Hematol Oncol 2019 Apr;41(3):e167-e170. doi: 10.1097/MPH.0000000000001245. PMID: 30028823
Sharma S, Dey P, Mitra S, Rajwanshi A, Nijhawan R, Srinivasan R, Gupta N, Das A
Cancer Cytopathol 2017 Feb;125(2):104-113. Epub 2016 Nov 21 doi: 10.1002/cncy.21799. PMID: 27870472
Gibson B, Podoll MB, Baumgartner EM, Maley DH
Ann Clin Lab Sci 2016 Spring;46(2):219-21. PMID: 27098632
Maeshima AM, Taniguchi H, Miyamoto K, Fukuhara S, Munakata W, Maruyama D, Kim SW, Kobayashi Y, Tobinai K, Kushima R
Pathol Int 2014 Aug;64(8):382-7. doi: 10.1111/pin.12186. PMID: 25143126

Therapy

Orsini A, Bernasconi S, Bianchi MC, Trivelli I, Menconi MC, Nardi M, Santangelo A, Casazza G, Carli N, Esposito MG, Peroni D, Striano P, Foiadelli T, Bonuccelli A
Acta Biomed 2022 Mar 21;92(S4):e2021416. doi: 10.23750/abm.v92iS4.12665. PMID: 35441608Free PMC Article
Swart L, Novitzky N, Mohamed Z, Opie J
Ann Hematol 2019 Feb;98(2):381-389. Epub 2018 Nov 5 doi: 10.1007/s00277-018-3533-0. PMID: 30397846
Rasmussen SL, Thomsen C
Diagn Pathol 2015 Apr 16;10:25. doi: 10.1186/s13000-015-0271-7. PMID: 25890312Free PMC Article
Minami J, Dobashi N, Asai O, Yano S, Osawa H, Takei Y, Yahagi Y, Takahara S, Ogasawara Y, Yamaguchi Y, Kobayashi T, Morikawa N, Nikaido T, Aiba K, Usui N
J Clin Exp Hematop 2010;50(2):143-9. doi: 10.3960/jslrt.50.143. PMID: 21123972

Prognosis

Oswald MS, Wurzel P, Hansmann ML
Acta Histochem 2019 Oct;121(7):769-775. Epub 2019 Jul 5 doi: 10.1016/j.acthis.2019.07.002. PMID: 31285059
Swart L, Novitzky N, Mohamed Z, Opie J
Ann Hematol 2019 Feb;98(2):381-389. Epub 2018 Nov 5 doi: 10.1007/s00277-018-3533-0. PMID: 30397846
Sharma S, Dey P, Mitra S, Rajwanshi A, Nijhawan R, Srinivasan R, Gupta N, Das A
Cancer Cytopathol 2017 Feb;125(2):104-113. Epub 2016 Nov 21 doi: 10.1002/cncy.21799. PMID: 27870472
Rasmussen SL, Thomsen C
Diagn Pathol 2015 Apr 16;10:25. doi: 10.1186/s13000-015-0271-7. PMID: 25890312Free PMC Article
Maeshima AM, Taniguchi H, Miyamoto K, Fukuhara S, Munakata W, Maruyama D, Kim SW, Kobayashi Y, Tobinai K, Kushima R
Pathol Int 2014 Aug;64(8):382-7. doi: 10.1111/pin.12186. PMID: 25143126

Clinical prediction guides

Rasmussen SL, Thomsen C
Diagn Pathol 2015 Apr 16;10:25. doi: 10.1186/s13000-015-0271-7. PMID: 25890312Free PMC Article
Maeshima AM, Taniguchi H, Miyamoto K, Fukuhara S, Munakata W, Maruyama D, Kim SW, Kobayashi Y, Tobinai K, Kushima R
Pathol Int 2014 Aug;64(8):382-7. doi: 10.1111/pin.12186. PMID: 25143126
Akhtar SS, Haque IU, Wafa SM, El-Saka H, Saroor AM, Nadrah HM
Saudi Med J 2009 May;30(5):677-81. PMID: 19417969

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Pediatric Hodgkin Lymphoma, 2024

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