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Hypopharynx cancer

MedGen UID:
102266
Concept ID:
C0153398
Neoplastic Process
Synonyms: Cancer, Hypopharyngeal; Cancers, Hypopharyngeal; Hypopharyngeal Cancer; Hypopharyngeal Cancers
SNOMED CT: Malignant tumor of laryngopharynx (363399006); Malignant neoplasm of laryngopharynx (363399006); Malignant tumor of hypopharynx (363399006)
 
Monarch Initiative: MONDO:0005806

Definition

A primary or metastatic malignant neoplasm that affects the hypopharynx. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypopharynx cancer

Professional guidelines

PubMed

Pointreau Y, Biau J, Delaby N, Thariat J, Lapeyre M
Cancer Radiother 2022 Feb-Apr;26(1-2):199-205. Epub 2021 Dec 22 doi: 10.1016/j.canrad.2021.10.006. PMID: 34953703
Siddiq S, Paleri V
Adv Otorhinolaryngol 2019;83:90-108. Epub 2019 Feb 12 doi: 10.1159/000492316. PMID: 30943516
McMullen CP, Smith RV
Surg Oncol Clin N Am 2015 Jul;24(3):521-45. Epub 2015 Apr 15 doi: 10.1016/j.soc.2015.03.013. PMID: 25979398

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

Recent clinical studies

Etiology

Johnson M, Porterfield JZ, Kejner AE
Otolaryngol Head Neck Surg 2022 Feb;166(2):282-288. Epub 2021 Jun 15 doi: 10.1177/01945998211020310. PMID: 34126807
Tseng CM, Wang HH, Lee CT, Tai CM, Tseng CH, Chen CC, Tsai YN, Chen TH, Hsu MH, Wang CC, Hwang TZ, Wang HP, Wang WL
Sci Rep 2020 Jan 21;10(1):884. doi: 10.1038/s41598-020-57630-6. PMID: 31964952Free PMC Article
Antunes HS, Herchenhorn D, Small IA, Araújo CMM, Viégas CMP, de Assis Ramos G, Dias FL, Ferreira CG
Oral Oncol 2017 Aug;71:11-15. Epub 2017 Jun 3 doi: 10.1016/j.oraloncology.2017.05.018. PMID: 28688677
Hamoir M, Fievez J, Schmitz S, Velasco D, Lengele B
Head Neck 2013 Oct;35(10):1482-9. Epub 2012 Sep 28 doi: 10.1002/hed.23174. PMID: 23018919
Chedid HM, Franzi SA, Rapoport A, Curioni OA
Rev Col Bras Cir 2010 Dec;37(6):385-9. doi: 10.1590/s0100-69912010000600002. PMID: 21340251

Diagnosis

Johnson M, Porterfield JZ, Kejner AE
Otolaryngol Head Neck Surg 2022 Feb;166(2):282-288. Epub 2021 Jun 15 doi: 10.1177/01945998211020310. PMID: 34126807
Burbure N, Handorf E, Ridge JA, Bauman J, Liu JC, Giri A, Galloway TJ
Head Neck 2021 Oct;43(10):3042-3052. Epub 2021 Jun 24 doi: 10.1002/hed.26793. PMID: 34165223Free PMC Article
Kwon HK, Han KD, Cheon YI, Shin SC, Lee M, Sung ES, Lee JC, Lee BJ
Sci Rep 2021 Feb 18;11(1):4174. doi: 10.1038/s41598-021-83665-4. PMID: 33603026Free PMC Article
Likhterov I, Ru M, Ganz C, Urken ML, Chai R, Okay D, Liu J, Stewart R, Culliney B, Palacios D, Lazarus CL
Laryngoscope 2018 Dec;128(12):2732-2739. Epub 2018 Oct 16 doi: 10.1002/lary.27224. PMID: 30325025Free PMC Article
Antunes HS, Herchenhorn D, Small IA, Araújo CMM, Viégas CMP, de Assis Ramos G, Dias FL, Ferreira CG
Oral Oncol 2017 Aug;71:11-15. Epub 2017 Jun 3 doi: 10.1016/j.oraloncology.2017.05.018. PMID: 28688677

Therapy

Karaüzüm K, Gökçek MD, Kalaş B, Karaüzüm İ, Ural E
Turk Kardiyol Dern Ars 2023 Jan;51(1):72-75. Epub 2022 Aug 17 doi: 10.5543/tkda.2022.28589. PMID: 36689292
Hamoir M, Fievez J, Schmitz S, Velasco D, Lengele B
Head Neck 2013 Oct;35(10):1482-9. Epub 2012 Sep 28 doi: 10.1002/hed.23174. PMID: 23018919
Kopac S, Jereb B
Pediatr Hematol Oncol 2004 Jan-Feb;21(1):17-21. PMID: 14660302
Pfister DG, Shaha AR, Harrison LB
Surg Oncol Clin N Am 1997 Oct;6(4):749-68. PMID: 9309092
Maier H, Sennewald E, Heller GF, Weidauer H
Otolaryngol Head Neck Surg 1994 Feb;110(2):168-73. doi: 10.1177/019459989411000205. PMID: 7906410

Prognosis

Johnson M, Porterfield JZ, Kejner AE
Otolaryngol Head Neck Surg 2022 Feb;166(2):282-288. Epub 2021 Jun 15 doi: 10.1177/01945998211020310. PMID: 34126807
Chabrillac E, Chaput B, Vergez S
Eur Arch Otorhinolaryngol 2020 Sep;277(9):2641-2645. Epub 2020 May 20 doi: 10.1007/s00405-020-06056-x. PMID: 32435851
Tseng CM, Wang HH, Lee CT, Tai CM, Tseng CH, Chen CC, Tsai YN, Chen TH, Hsu MH, Wang CC, Hwang TZ, Wang HP, Wang WL
Sci Rep 2020 Jan 21;10(1):884. doi: 10.1038/s41598-020-57630-6. PMID: 31964952Free PMC Article
Hamoir M, Fievez J, Schmitz S, Velasco D, Lengele B
Head Neck 2013 Oct;35(10):1482-9. Epub 2012 Sep 28 doi: 10.1002/hed.23174. PMID: 23018919
Pfister DG, Shaha AR, Harrison LB
Surg Oncol Clin N Am 1997 Oct;6(4):749-68. PMID: 9309092

Clinical prediction guides

Johnson M, Porterfield JZ, Kejner AE
Otolaryngol Head Neck Surg 2022 Feb;166(2):282-288. Epub 2021 Jun 15 doi: 10.1177/01945998211020310. PMID: 34126807
Galeano Machuca MP, Ng DL, Terng SD, Wu WC, Cheng CT
J Surg Oncol 2021 Jun;123(7):1540-1546. Epub 2021 Feb 23 doi: 10.1002/jso.26440. PMID: 33621353
Santos ASE, Martins AAF, Simões Gonçalves E, Meyer A
Asian Pac J Cancer Prev 2020 Jun 1;21(6):1779-1786. doi: 10.31557/APJCP.2020.21.6.1779. PMID: 32592378Free PMC Article
Arends CR, Petersen JF, van der Noort V, Timmermans AJ, Leemans CR, de Bree R, van den Brekel MWM, Stuiver MM
Laryngoscope 2020 Sep;130(9):2166-2172. Epub 2019 Nov 6 doi: 10.1002/lary.28345. PMID: 31693181Free PMC Article
Likhterov I, Ru M, Ganz C, Urken ML, Chai R, Okay D, Liu J, Stewart R, Culliney B, Palacios D, Lazarus CL
Laryngoscope 2018 Dec;128(12):2732-2739. Epub 2018 Oct 16 doi: 10.1002/lary.27224. PMID: 30325025Free PMC Article

Recent systematic reviews

Wulff NB, Højager A, Wessel I, Dalton SO, Homøe P
Laryngoscope 2021 Apr;131(4):820-831. Epub 2020 Aug 31 doi: 10.1002/lary.29027. PMID: 32866284

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

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