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Metastatic Malignant Neoplasm in the Kidney

MedGen UID:
102286
Concept ID:
C0153685
Neoplastic Process
Synonyms: Cancer metastatic to kidney; Metastases to Kidney; Metastases to the Kidney; Metastasis to Kidney; Metastasis to renal parenchyma; Metastasis to the Kidney; Metastatic malignant neoplasm of kidney; Metastatic malignant neoplasm to kidney; Metastatic Malignant Neoplasm to the Kidney; Metastatic Neoplasm to the Kidney; Metastatic tumor in kidney; Metastatic Tumor to the Kidney; Renal Metastases; Renal metastasis; Renal Metastasis; Secondary cancer of kidney; Secondary malignant neoplasm of kidney; Secondary renal cancer
SNOMED CT: Metastatic tumor in kidney (94360002); Metastasis to renal parenchyma (94360002); Secondary renal cancer (94360002); Renal metastasis (94360002); Secondary cancer of kidney (94360002); Secondary malignant neoplasm of kidney (94360002); Metastatic malignant neoplasm to kidney (94360002); Cancer metastatic to kidney (94360002); Metastatic malignant neoplasm of kidney (94360002)

Definition

The spread of a malignant neoplasm to the kidney. This may be from a primary kidney malignant neoplasm involving the opposite kidney, or from a malignant neoplasm at a distant site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Kidney

Professional guidelines

PubMed

Cabanillas G, Montoya-Cerrillo D, Kryvenko ON, Pal SK, Arias-Stella JA 3rd
Urol Oncol 2022 Dec;40(12):525-536. Epub 2021 Jun 8 doi: 10.1016/j.urolonc.2021.04.041. PMID: 34116936
Teyssonneau D, Gross-Goupil M, Domblides C, Haaser T, Pointillart V, Daste A, Hauger O, Ravaud A
Crit Rev Oncol Hematol 2018 May;125:19-29. Epub 2018 Mar 6 doi: 10.1016/j.critrevonc.2018.02.017. PMID: 29650272
Junker K, Ficarra V, Kwon ED, Leibovich BC, Thompson RH, Oosterwijk E
Eur Urol 2013 Feb;63(2):333-40. Epub 2012 Sep 24 doi: 10.1016/j.eururo.2012.09.040. PMID: 23040205

Recent clinical studies

Etiology

Motzer RJ, Russo P, Grünwald V, Tomita Y, Zurawski B, Parikh O, Buti S, Barthélémy P, Goh JC, Ye D, Lingua A, Lattouf JB, Albigès L, George S, Shuch B, Sosman J, Staehler M, Vázquez Estévez S, Simsek B, Spiridigliozzi J, Chudnovsky A, Bex A
Lancet 2023 Mar 11;401(10379):821-832. Epub 2023 Feb 9 doi: 10.1016/S0140-6736(22)02574-0. PMID: 36774933Free PMC Article
Fernandes-Rosa FL, Boulkroun S, Fedlaoui B, Hureaux M, Travers-Allard S, Drossart T, Favier J, Zennaro MC
Kidney Int 2023 Mar;103(3):485-500. Epub 2023 Jan 13 doi: 10.1016/j.kint.2022.12.021. PMID: 36646167
de Francisco ALM, Macía M, Alonso F, García P, Gutierrez E, Quintana LF, Quiroga B, Torregrosa I
Nefrologia (Engl Ed) 2019 Sep-Oct;39(5):473-481. Epub 2019 Mar 29 doi: 10.1016/j.nefro.2018.10.016. PMID: 30929891
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article
Ravaud A, Motzer RJ, Pandha HS, George DJ, Pantuck AJ, Patel A, Chang YH, Escudier B, Donskov F, Magheli A, Carteni G, Laguerre B, Tomczak P, Breza J, Gerletti P, Lechuga M, Lin X, Martini JF, Ramaswamy K, Casey M, Staehler M, Patard JJ; S-TRAC Investigators
N Engl J Med 2016 Dec 8;375(23):2246-2254. Epub 2016 Oct 9 doi: 10.1056/NEJMoa1611406. PMID: 27718781

Diagnosis

Cabanillas G, Montoya-Cerrillo D, Kryvenko ON, Pal SK, Arias-Stella JA 3rd
Urol Oncol 2022 Dec;40(12):525-536. Epub 2021 Jun 8 doi: 10.1016/j.urolonc.2021.04.041. PMID: 34116936
Cox RM, Magi-Galluzzi C, McKenney JK
Adv Anat Pathol 2018 Nov;25(6):387-399. doi: 10.1097/PAP.0000000000000205. PMID: 30157041
Omiyale AO, Carton J
Curr Urol Rep 2018 Jan 31;19(2):4. doi: 10.1007/s11934-018-0755-6. PMID: 29383452
Corgna E, Betti M, Gatta G, Roila F, De Mulder PH
Crit Rev Oncol Hematol 2007 Dec;64(3):247-62. Epub 2007 Jul 26 doi: 10.1016/j.critrevonc.2007.04.007. PMID: 17662611
Greifenkamp JD, DiPette DJ
Curr Hypertens Rep 1999 Jun;1(3):241-5. doi: 10.1007/s11906-999-0028-3. PMID: 10981073

Therapy

Albiges L, Gurney H, Atduev V, Suarez C, Climent MA, Pook D, Tomczak P, Barthelemy P, Lee JL, Stus V, Ferguson T, Wiechno P, Gokmen E, Lacombe L, Gedye C, Perini RF, Sharma M, Peng X, Lee CH
Lancet Oncol 2023 Aug;24(8):881-891. Epub 2023 Jul 11 doi: 10.1016/S1470-2045(23)00276-0. PMID: 37451291
Siva S, Ali M, Correa RJM, Muacevic A, Ponsky L, Ellis RJ, Lo SS, Onishi H, Swaminath A, McLaughlin M, Morgan SC, Cury FL, Teh BS, Mahadevan A, Kaplan ID, Chu W, Grubb W, Hannan R, Staehler M, Warner A, Louie AV
Lancet Oncol 2022 Dec;23(12):1508-1516. Epub 2022 Nov 16 doi: 10.1016/S1470-2045(22)00656-8. PMID: 36400098
de Francisco ALM, Macía M, Alonso F, García P, Gutierrez E, Quintana LF, Quiroga B, Torregrosa I
Nefrologia (Engl Ed) 2019 Sep-Oct;39(5):473-481. Epub 2019 Mar 29 doi: 10.1016/j.nefro.2018.10.016. PMID: 30929891
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article
Ravaud A, Motzer RJ, Pandha HS, George DJ, Pantuck AJ, Patel A, Chang YH, Escudier B, Donskov F, Magheli A, Carteni G, Laguerre B, Tomczak P, Breza J, Gerletti P, Lechuga M, Lin X, Martini JF, Ramaswamy K, Casey M, Staehler M, Patard JJ; S-TRAC Investigators
N Engl J Med 2016 Dec 8;375(23):2246-2254. Epub 2016 Oct 9 doi: 10.1056/NEJMoa1611406. PMID: 27718781

Prognosis

Karam S, Haidous M, Royal V, Leung N
Kidney Int 2023 Mar;103(3):473-484. Epub 2022 Dec 9 doi: 10.1016/j.kint.2022.10.028. PMID: 36502873
Alchahin AM, Mei S, Tsea I, Hirz T, Kfoury Y, Dahl D, Wu CL, Subtelny AO, Wu S, Scadden DT, Shin JH, Saylor PJ, Sykes DB, Kharchenko PV, Baryawno N
Nat Commun 2022 Sep 30;13(1):5747. doi: 10.1038/s41467-022-33375-w. PMID: 36180422Free PMC Article
Roussel E, Capitanio U, Kutikov A, Oosterwijk E, Pedrosa I, Rowe SP, Gorin MA
Eur Urol 2022 May;81(5):476-488. Epub 2022 Feb 22 doi: 10.1016/j.eururo.2022.01.040. PMID: 35216855Free PMC Article
Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article

Clinical prediction guides

Alchahin AM, Mei S, Tsea I, Hirz T, Kfoury Y, Dahl D, Wu CL, Subtelny AO, Wu S, Scadden DT, Shin JH, Saylor PJ, Sykes DB, Kharchenko PV, Baryawno N
Nat Commun 2022 Sep 30;13(1):5747. doi: 10.1038/s41467-022-33375-w. PMID: 36180422Free PMC Article
Pianou NK, Stavrou PZ, Vlontzou E, Rondogianni P, Exarhos DN, Datseris IE
Hell J Nucl Med 2019 Jan-Apr;22(1):6-9. Epub 2019 Mar 7 doi: 10.1967/s002449910952. PMID: 30843003
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article
Junker K, Ficarra V, Kwon ED, Leibovich BC, Thompson RH, Oosterwijk E
Eur Urol 2013 Feb;63(2):333-40. Epub 2012 Sep 24 doi: 10.1016/j.eururo.2012.09.040. PMID: 23040205
Gillams A
Cancer Imaging 2009 Oct 2;9 Spec No A(Special issue A):S68-70. doi: 10.1102/1470-7330.2009.9028. PMID: 19965298Free PMC Article

Recent systematic reviews

Scalia G, Silven MP, Costanzo R, Porzio M, Maugeri R, Iacopino DG, Nicoletti GF, Umana GE
Anticancer Res 2024 Feb;44(2):453-462. doi: 10.21873/anticanres.16833. PMID: 38307552
Sharma G, Kakkar N, Singh SK, Parmar K, Sharma AP, Mavuduru R
Int J Clin Pract 2021 Dec;75(12):e14971. Epub 2021 Oct 20 doi: 10.1111/ijcp.14971. PMID: 34626514
Blas L, Roberti J
Curr Urol Rep 2021 Mar 11;22(4):25. doi: 10.1007/s11934-021-01038-w. PMID: 33704587
Mir MC, Derweesh I, Porpiglia F, Zargar H, Mottrie A, Autorino R
Eur Urol 2017 Apr;71(4):606-617. Epub 2016 Sep 7 doi: 10.1016/j.eururo.2016.08.060. PMID: 27614693
Rai BP, Shelley M, Coles B, Biyani CS, El-Mokadem I, Nabi G
Cochrane Database Syst Rev 2011 Apr 13;(4):CD007349. doi: 10.1002/14651858.CD007349.pub2. PMID: 21491399

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