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Benign neoplasm of floor of mouth

MedGen UID:
102295
•Concept ID:
C0153934
•
Neoplastic Process
Synonyms: Benign Floor of Mouth Neoplasm; benign floor of mouth neoplasm; Benign Floor of Mouth Tumor; benign floor of mouth tumor; benign floor of mouth tumour; Benign Floor of the Mouth Neoplasm; benign floor of the mouth neoplasm; Benign Floor of the Mouth Tumor; benign floor of the mouth tumor; benign floor of the mouth tumour; Benign Neoplasm of Floor of Mouth; benign neoplasm of floor of mouth; Benign Neoplasm of the Floor of the Mouth; benign neoplasm of the floor of the mouth; Benign tumor of floor of mouth; Benign Tumor of Floor of Mouth; benign tumor of floor of mouth; Benign Tumor of the Floor of the Mouth; benign tumor of the floor of the mouth; benign tumour of floor of mouth; benign tumour of the floor of the mouth; FOM - Benign tumor of floor of mouth; mouth floor benign neoplasm
SNOMED CT: Benign neoplasm of floor of mouth (92109005); Benign tumor of floor of mouth (92109005); FOM - Benign tumor of floor of mouth (92109005)
 
Monarch Initiative: MONDO:0021520

Definition

A neoplasm that arises from the floor of the mouth and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of floor of mouth

Professional guidelines

PubMed

Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology.
Henry M
Curr Oncol 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501. PMID: 37504361Free PMC Article
Management of Mucoceles, Sialoceles, and Ranulas.
Bowers EMR, Schaitkin B
Otolaryngol Clin North Am 2021 Jun;54(3):543-551. doi: 10.1016/j.otc.2021.03.002. PMID: 34024482
Diagnosis and management of congenital floor of mouth masses: A systematic review.
Lucas JP, Allen M, Siegel B, Gonik N
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110541. Epub 2020 Dec 1 doi: 10.1016/j.ijporl.2020.110541. PMID: 33296834

Recent clinical studies

Etiology

Diagnosis and management of hypoglossal nerve-derived schwannoma in the floor of mouth: a case series.
Zhong J, Zhou Z, Hu Y, Zhao T, Yao Y, Zhong L, Zhu D
BMC Oral Health 2022 Jun 29;22(1):265. doi: 10.1186/s12903-022-02302-2. PMID: 35768820Free PMC Article
Brachytherapy with (198)Au grains for cancer of the floor of the mouth: relationships between radiation dose and complications.
Konishi M, Takeuchi Y, Imano N, Kubo K, Nishibuchi I, Murakami Y, Shimabukuro K, Wongratwanich P, Kakimoto N, Nagata Y
Oral Radiol 2022 Jan;38(1):105-113. Epub 2021 May 11 doi: 10.1007/s11282-021-00532-8. PMID: 33973086
Diagnosis and management of congenital floor of mouth masses: A systematic review.
Lucas JP, Allen M, Siegel B, Gonik N
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110541. Epub 2020 Dec 1 doi: 10.1016/j.ijporl.2020.110541. PMID: 33296834
Operative tactics in floor of mouth and tongue cancer resection - the importance of imaging and planning.
McMahon J, Steele P, Kyzas P, Pollard C, Jampana R, MacIver C, Subramaniam S, Devine J, Wales C, McCaul J
Br J Oral Maxillofac Surg 2021 Jan;59(1):5-15. Epub 2020 Oct 4 doi: 10.1016/j.bjoms.2020.08.118. PMID: 33143945
Compartmental surgery for oral tongue and floor of the mouth cancer: Oncologic outcomes.
Piazza C, Grammatica A, Montalto N, Paderno A, Del Bon F, Nicolai P
Head Neck 2019 Jan;41(1):110-115. Epub 2018 Dec 11 doi: 10.1002/hed.25480. PMID: 30536781

Diagnosis

Craniofacial Epidermoid and Dermoid Cysts.
Oh HJ, Eo MY, Sodnom-Ish B, Amponsah EK, Frimpong P, Myoung H, Kim SM
J Craniofac Surg 2023 Nov-Dec 01;34(8):2405-2409. Epub 2023 Jul 24 doi: 10.1097/SCS.0000000000009561. PMID: 37487139Free PMC Article
Pleomorphic adenoma of hard palate: a case report.
Yousra Z, Saliha C
Pan Afr Med J 2021;38:146. Epub 2021 Feb 9 doi: 10.11604/pamj.2021.38.146.26508. PMID: 33912316Free PMC Article
Imaging the floor of the mouth and the sublingual space.
La'porte SJ, Juttla JK, Lingam RK
Radiographics 2011 Sep-Oct;31(5):1215-30. doi: 10.1148/rg.315105062. PMID: 21918039
Oral cavity cancer.
Kirsch C
Top Magn Reson Imaging 2007 Aug;18(4):269-80. doi: 10.1097/RMR.0b013e3181572caa. PMID: 17893592
Salivary glands.
Saunders JR Jr, Hirata RM, Jaques DA
Surg Clin North Am 1986 Feb;66(1):59-81. doi: 10.1016/s0039-6109(16)43829-6. PMID: 3003940

Therapy

Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.
Lorenzo-Pouso AI, Lafuente-Ibáñez de Mendoza I, Pérez-Sayáns M, Pérez-Jardón A, Chamorro-Petronacci CM, Blanco-Carrión A, Aguirre-Urízar JM
J Oral Pathol Med 2022 Aug;51(7):585-593. Epub 2022 May 12 doi: 10.1111/jop.13304. PMID: 35488780Free PMC Article
Brachytherapy with (198)Au grains for cancer of the floor of the mouth: relationships between radiation dose and complications.
Konishi M, Takeuchi Y, Imano N, Kubo K, Nishibuchi I, Murakami Y, Shimabukuro K, Wongratwanich P, Kakimoto N, Nagata Y
Oral Radiol 2022 Jan;38(1):105-113. Epub 2021 May 11 doi: 10.1007/s11282-021-00532-8. PMID: 33973086
Dose escalation in advanced floor of the mouth cancer: a pilot study using a combination of IMRT and stereotactic boost.
Blažek T, Zděblová Čermáková Z, Knybel L, Hurník P, Štembírek J, Resová K, Paračková T, Formánek M, Cvek J, Soumarová R
Radiat Oncol 2021 Jun 29;16(1):122. doi: 10.1186/s13014-021-01842-1. PMID: 34187494Free PMC Article
A worldwide comparison of the management of surgical treatment of advanced oral cancer.
Kansy K, Mueller AA, Mücke T, Koersgen F, Wolff KD, Zeilhofer HF, Hölzle F, Pradel W, Schneider M, Kolk A, Smeets R, Acero J, Haers P, Ghali GE, Hoffmann J
J Craniomaxillofac Surg 2018 Mar;46(3):511-520. Epub 2018 Jan 8 doi: 10.1016/j.jcms.2017.12.031. PMID: 29395993
Oral graft-versus-host disease.
Kuten-Shorrer M, Woo SB, Treister NS
Dent Clin North Am 2014 Apr;58(2):351-68. doi: 10.1016/j.cden.2013.12.007. PMID: 24655527

Prognosis

Malignant fibrous histiocytoma of the floor of mouth: a case report and review of the literature.
Wu Y, Liu X, Lv Y, Li Z
J Stomatol Oral Maxillofac Surg 2022 Jun;123(3):e106-e111. Epub 2021 Jul 2 doi: 10.1016/j.jormas.2021.06.017. PMID: 34224923
Diagnosis and management of congenital floor of mouth masses: A systematic review.
Lucas JP, Allen M, Siegel B, Gonik N
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110541. Epub 2020 Dec 1 doi: 10.1016/j.ijporl.2020.110541. PMID: 33296834
Results of postoperative interstitial brachytherapy of resectable floor of mouth tumors.
Ferenczi Ö, Major T, Akiyama H, Fröhlich G, Oberna F, Révész M, Poósz M, Polgár C, Takácsi-Nagy Z
Brachytherapy 2021 Mar-Apr;20(2):376-382. Epub 2020 Nov 26 doi: 10.1016/j.brachy.2020.10.008. PMID: 33250304
Operative tactics in floor of mouth and tongue cancer resection - the importance of imaging and planning.
McMahon J, Steele P, Kyzas P, Pollard C, Jampana R, MacIver C, Subramaniam S, Devine J, Wales C, McCaul J
Br J Oral Maxillofac Surg 2021 Jan;59(1):5-15. Epub 2020 Oct 4 doi: 10.1016/j.bjoms.2020.08.118. PMID: 33143945
Compartmental surgery for oral tongue and floor of the mouth cancer: Oncologic outcomes.
Piazza C, Grammatica A, Montalto N, Paderno A, Del Bon F, Nicolai P
Head Neck 2019 Jan;41(1):110-115. Epub 2018 Dec 11 doi: 10.1002/hed.25480. PMID: 30536781

Clinical prediction guides

Clinical predictors of malignant transformation and recurrence in oral potentially malignant disorders: A systematic review and meta-analysis.
Paglioni MP, Khurram SA, Ruiz BII, Lauby-Secretan B, Normando AG, Ribeiro ACP, Brandão TB, Palmier NR, Lopes MA, da Silva Guerra EN, Meleti M, Migliorati CA, Carvalho AL, de Matos LL, Kowalski LP, Santos-Silva AR
Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Nov;134(5):573-587. Epub 2022 Jul 21 doi: 10.1016/j.oooo.2022.07.006. PMID: 36153299
Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.
Lorenzo-Pouso AI, Lafuente-Ibáñez de Mendoza I, Pérez-Sayáns M, Pérez-Jardón A, Chamorro-Petronacci CM, Blanco-Carrión A, Aguirre-Urízar JM
J Oral Pathol Med 2022 Aug;51(7):585-593. Epub 2022 May 12 doi: 10.1111/jop.13304. PMID: 35488780Free PMC Article
Oral Adult Rhabdomyoma.
da Silva Leonel ACL, Dos Santos ST, de Amorim Carvalho EJ, de Castro JFL, de Almeida OP, da Cruz Perez DE
Head Neck Pathol 2021 Dec;15(4):1253-1260. Epub 2021 Aug 10 doi: 10.1007/s12105-021-01371-z. PMID: 34378165Free PMC Article
Results of postoperative interstitial brachytherapy of resectable floor of mouth tumors.
Ferenczi Ö, Major T, Akiyama H, Fröhlich G, Oberna F, Révész M, Poósz M, Polgár C, Takácsi-Nagy Z
Brachytherapy 2021 Mar-Apr;20(2):376-382. Epub 2020 Nov 26 doi: 10.1016/j.brachy.2020.10.008. PMID: 33250304
Axillary lymph node metastasis in second oropharyngeal cancer.
Alessandro S, Magremanne M, Marbaix E, Reychler H, Mahy P
J Stomatol Oral Maxillofac Surg 2019 Apr;120(2):160-163. Epub 2018 Nov 1 doi: 10.1016/j.jormas.2018.10.010. PMID: 30391374

Recent systematic reviews

Clinical predictors of malignant transformation and recurrence in oral potentially malignant disorders: A systematic review and meta-analysis.
Paglioni MP, Khurram SA, Ruiz BII, Lauby-Secretan B, Normando AG, Ribeiro ACP, Brandão TB, Palmier NR, Lopes MA, da Silva Guerra EN, Meleti M, Migliorati CA, Carvalho AL, de Matos LL, Kowalski LP, Santos-Silva AR
Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Nov;134(5):573-587. Epub 2022 Jul 21 doi: 10.1016/j.oooo.2022.07.006. PMID: 36153299
Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder.
Lorenzo-Pouso AI, Lafuente-Ibáñez de Mendoza I, Pérez-Sayáns M, Pérez-Jardón A, Chamorro-Petronacci CM, Blanco-Carrión A, Aguirre-Urízar JM
J Oral Pathol Med 2022 Aug;51(7):585-593. Epub 2022 May 12 doi: 10.1111/jop.13304. PMID: 35488780Free PMC Article
Cribriform adenocarcinoma of the tongue and minor salivary glands: a systematic review of an uncommon clinicopathological entity.
De Luca P, Tassone D, de Campora L, Simone M, Marra P, Colacurcio V, Scarpa A, Costarelli L, Camaioni A
Eur Arch Otorhinolaryngol 2022 Jun;279(6):2719-2725. Epub 2021 Oct 23 doi: 10.1007/s00405-021-07140-6. PMID: 34687340
Diagnosis and management of congenital floor of mouth masses: A systematic review.
Lucas JP, Allen M, Siegel B, Gonik N
Int J Pediatr Otorhinolaryngol 2021 Jan;140:110541. Epub 2020 Dec 1 doi: 10.1016/j.ijporl.2020.110541. PMID: 33296834
Systematic review of the platysma myocutaneous flap for head and neck reconstruction.
Szudek J, Taylor SM
Arch Otolaryngol Head Neck Surg 2007 Jul;133(7):655-61. doi: 10.1001/archotol.133.7.655. PMID: 17638777

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