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Cervical benign neoplasm

MedGen UID:
102300
Concept ID:
C0153997
Neoplastic Process
Synonyms: Benign Cervical Neoplasm; benign cervical neoplasm; Benign Cervix Uteri Neoplasm; benign cervix uteri neoplasm; Benign Cervix Uteri Neoplasm NOS; Benign Cervix Uteri Tumor; benign cervix uteri tumor; benign cervix uteri tumour; Benign neoplasm of cervix uteri; Benign Neoplasm of Cervix Uteri; benign neoplasm of cervix uteri; Benign Neoplasm of the Cervix Uteri; benign neoplasm of the cervix uteri; Benign Neoplasm of the Uterine Cervix; benign neoplasm of the uterine cervix; Benign neoplasm of uterine cervix; Benign Neoplasm of Uterine Cervix; benign neoplasm of uterine cervix; Benign tumor of cervix; Benign Tumor of Cervix Uteri; benign tumor of cervix uteri; Benign Tumor of the Cervix Uteri; benign tumor of the cervix uteri; Benign Tumor of the Uterine Cervix; benign tumor of the uterine cervix; Benign Tumor of Uterine Cervix; benign tumor of uterine cervix; benign tumour of cervix uteri; benign tumour of the cervix uteri; benign tumour of the uterine cervix; benign tumour of uterine cervix; Benign Uterine Cervix Neoplasm; benign uterine cervix neoplasm; Benign Uterine Cervix Tumor; benign uterine cervix tumor; benign uterine cervix tumour; cervical benign neoplasm; uterine cervix benign neoplasm
SNOMED CT: Benign tumor of cervix (92056006); Benign neoplasm of uterine cervix (92056006); Benign neoplasm of cervix uteri (92056006)
 
Monarch Initiative: MONDO:0000644

Definition

A neoplasm that arises from the cervix and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include squamous papilloma, endocervical polyp, and rhabdomyoma. [from NCI]

Professional guidelines

PubMed

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Owen JL, Kibbi N, Worley B, Kelm RC, Wang JV, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw SH, Cartee TV, Chandra S, Cho NL, Choi JN, Council ML, Demirci H, Eisen DB, Esmaeli B, Golda N, Huang CC, Ibrahim SF, Jiang SB, Kim J, Kuzel TM, Lai SY, Lawrence N, Lee EH, Leitenberger JJ, Maher IA, Mann MW, Minkis K, Mittal BB, Nehal KS, Neuhaus IM, Ozog DM, Petersen B, Rotemberg V, Samant S, Samie FH, Servaes S, Shields CL, Shin TM, Sobanko JF, Somani AK, Stebbins WG, Thomas JR, Thomas VD, Tse DT, Waldman AH, Wong MK, Xu YG, Yu SS, Zeitouni NC, Ramsay T, Reynolds KA, Poon E, Alam M
Lancet Oncol 2019 Dec;20(12):e699-e714. doi: 10.1016/S1470-2045(19)30673-4. PMID: 31797796
Filetti S, Durante C, Hartl D, Leboulleux S, Locati LD, Newbold K, Papotti MG, Berruti A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2019 Dec 1;30(12):1856-1883. doi: 10.1093/annonc/mdz400. PMID: 31549998

Recent clinical studies

Etiology

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Vrînceanu D, Sajin M, Dumitru M, Mogoantă CA, Cergan R, Georgescu MG
Rom J Morphol Embryol 2022 Jul-Sep;63(3):485-490. doi: 10.47162/RJME.63.3.02. PMID: 36588486Free PMC Article
Pupić-Bakrač J, Pupić-Bakrač A, Novaković J, Skitarelić N
J Craniofac Surg 2021 Jun 1;32(4):1417-1420. doi: 10.1097/SCS.0000000000007122. PMID: 33170821
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855

Diagnosis

Kobayashi K, Hanai N, Yoshimoto S, Saito Y, Homma A
Jpn J Clin Oncol 2023 Aug 30;53(9):743-756. doi: 10.1093/jjco/hyad048. PMID: 37309253Free PMC Article
Liu Y, Housley Smith M, Patel PB, Bilodeau EA
Pediatr Dev Pathol 2023 Nov-Dec;26(6):621-641. Epub 2023 May 26 doi: 10.1177/10935266231170744. PMID: 37232383
Vrînceanu D, Sajin M, Dumitru M, Mogoantă CA, Cergan R, Georgescu MG
Rom J Morphol Embryol 2022 Jul-Sep;63(3):485-490. doi: 10.47162/RJME.63.3.02. PMID: 36588486Free PMC Article
López F, Suárez C, Vander Poorten V, Mäkitie A, Nixon IJ, Strojan P, Hanna EY, Rodrigo JP, de Bree R, Quer M, Takes RP, Bradford CR, Shaha AR, Sanabria A, Rinaldo A, Ferlito A
Head Neck 2019 Feb;41(2):522-535. Epub 2018 Dec 14 doi: 10.1002/hed.25439. PMID: 30549361
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417

Therapy

Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Gravitt PE
J Clin Invest 2011 Dec;121(12):4593-9. Epub 2011 Dec 1 doi: 10.1172/JCI57149. PMID: 22133884Free PMC Article
Sipos JA
Thyroid 2009 Dec;19(12):1363-72. doi: 10.1089/thy.2009.1608. PMID: 20001718
Lippman SM, Benner SE, Hong WK
J Clin Oncol 1994 Apr;12(4):851-73. doi: 10.1200/JCO.1994.12.4.851. PMID: 8151328

Prognosis

Wong BLK, Hogan C
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 4(Suppl 4):S177-S187. Epub 2022 May 20 doi: 10.1016/j.bjorl.2022.04.002. PMID: 35659712Free PMC Article
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Zanoni DK, Montero PH, Migliacci JC, Shah JP, Wong RJ, Ganly I, Patel SG
Oral Oncol 2019 Mar;90:115-121. Epub 2019 Feb 15 doi: 10.1016/j.oraloncology.2019.02.001. PMID: 30846169Free PMC Article
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Torre LA, Siegel RL, Ward EM, Jemal A
Cancer Epidemiol Biomarkers Prev 2016 Jan;25(1):16-27. Epub 2015 Dec 14 doi: 10.1158/1055-9965.EPI-15-0578. PMID: 26667886

Clinical prediction guides

Wishart LR, Ward EC, Galloway G
Curr Opin Otolaryngol Head Neck Surg 2023 Dec 1;31(6):368-373. Epub 2023 Aug 4 doi: 10.1097/MOO.0000000000000918. PMID: 37548514
Patel N, Kaleem A, Tursun R
J Oral Maxillofac Surg 2022 Jun;80(6):1127-1133. Epub 2022 Mar 16 doi: 10.1016/j.joms.2022.03.007. PMID: 35385707
Nachalon Y, Nativ-Zeltzer N, Evangelista LM, Dhar SI, Lin SJ, Shen SC, Belafsky PC
Laryngoscope 2021 Mar;131(3):548-552. Epub 2020 Jul 6 doi: 10.1002/lary.28880. PMID: 32628787
Strohl MP, El-Sayed IH
Curr Oncol Rep 2019 Nov 14;21(11):103. doi: 10.1007/s11912-019-0853-8. PMID: 31728649
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855

Recent systematic reviews

Banik K, Khatoon E, Harsha C, Rana V, Parama D, Thakur KK, Bishayee A, Kunnumakkara AB
Phytother Res 2022 May;36(5):1854-1883. Epub 2022 Jan 31 doi: 10.1002/ptr.7386. PMID: 35102626
Hanna TP, King WD, Thibodeau S, Jalink M, Paulin GA, Harvey-Jones E, O'Sullivan DE, Booth CM, Sullivan R, Aggarwal A
BMJ 2020 Nov 4;371:m4087. doi: 10.1136/bmj.m4087. PMID: 33148535Free PMC Article
Mohan G, Chattopadhyay S
JAMA Oncol 2020 Sep 1;6(9):1434-1444. doi: 10.1001/jamaoncol.2020.1460. PMID: 32556187Free PMC Article
Saei Ghare Naz M, Kariman N, Ebadi A, Ozgoli G, Ghasemi V, Rashidi Fakari F
Asian Pac J Cancer Prev 2018 Apr 25;19(4):875-884. doi: 10.22034/APJCP.2018.19.4.875. PMID: 29693331Free PMC Article
Arbyn M, Redman CWE, Verdoodt F, Kyrgiou M, Tzafetas M, Ghaem-Maghami S, Petry KU, Leeson S, Bergeron C, Nieminen P, Gondry J, Reich O, Moss EL
Lancet Oncol 2017 Dec;18(12):1665-1679. Epub 2017 Nov 7 doi: 10.1016/S1470-2045(17)30700-3. PMID: 29126708

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