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Pseudomembranous conjunctivitis

MedGen UID:
102325
•Concept ID:
C0155144
•
Disease or Syndrome
Synonyms: conjunctivitis with pseudomembrane; Pseudomembranous Conjunctivitis; pseudomembranous conjunctivitis
SNOMED CT: Pseudomembranous conjunctivitis (72115001)
 
Monarch Initiative: MONDO:0001217

Definition

Conjunctivitis that is characterized by formation of a pseudomembrane. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPseudomembranous conjunctivitis

Professional guidelines

PubMed

Acute intensive care unit management of mustard gas victims: the Turkish experience().
Kilic E, Ortatatli M, Sezigen S, Eyison RK, Kenar L
Cutan Ocul Toxicol 2018 Dec;37(4):332-337. Epub 2018 May 7 doi: 10.1080/15569527.2018.1464018. PMID: 29648477
Management of patients with ocular manifestations in vesiculobullous disorders affecting the mouth.
Hansen MS, Klefter ON, Julian HO, Lynge Pedersen AM, Heegaard S
Oral Dis 2017 Oct;23(7):849-853. Epub 2016 Nov 17 doi: 10.1111/odi.12590. PMID: 27717107
Etiology and diagnosis of neonatal conjunctivitis.
Sandström I
Acta Paediatr Scand 1987 Mar;76(2):221-7. doi: 10.1111/j.1651-2227.1987.tb10451.x. PMID: 3109205

Recent clinical studies

Etiology

Pediatric chronic graft-versus-host disease-related dry eye disease and the diagnostic association of potential clinical findings.
Yagi H, Shimizu E, Yagi R, Uchino M, Kamoi M, Asai K, Tsubota K, Negishi K, Ogawa Y
Sci Rep 2023 Mar 2;13(1):3575. doi: 10.1038/s41598-023-30288-6. PMID: 36864106Free PMC Article
Epidemiology of pseudomembranous conjunctivitis in a tertiary hospital: A 2-year retrospective study.
de-Arriba-Palomero F, Salvá-Palomeque T, de-Arriba-Palomero P, Arnalich-Montiel F
Eur J Ophthalmol 2021 Sep;31(5):2275-2279. Epub 2020 Sep 9 doi: 10.1177/1120672120957581. PMID: 32907398
Bristle Worm-Induced Keratouveitis: A Case Report.
Kirk J, Gunn D, Wong N, Minchin E, Darcy K
Cornea 2020 May;39(5):654-656. doi: 10.1097/ICO.0000000000002225. PMID: 31842040
Plasmapheresis, Intravenous Immunoglobulins, and Autologous Serum Eyedrops in the Acute Eye Complications of Toxic Epidermal Necrolysis.
Pinna A, Nuvoli E, Blasetti F, Posadinu MA, Boscia F
Eur J Ophthalmol 2017 Nov 8;27(6):658-663. doi: 10.5301/ejo.5000923. PMID: 28362052
Visual acuity and anterior segment findings in chronic graft-versus-host disease.
Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943

Diagnosis

Pseudomembranous conjunctivitis with hand, foot and mouth disease in a pregnant woman : a case report.
Kim YJ, Kim TG
BMC Ophthalmol 2021 Mar 2;21(1):113. doi: 10.1186/s12886-021-01878-7. PMID: 33653308Free PMC Article
Epidemiology of pseudomembranous conjunctivitis in a tertiary hospital: A 2-year retrospective study.
de-Arriba-Palomero F, Salvá-Palomeque T, de-Arriba-Palomero P, Arnalich-Montiel F
Eur J Ophthalmol 2021 Sep;31(5):2275-2279. Epub 2020 Sep 9 doi: 10.1177/1120672120957581. PMID: 32907398
Bristle Worm-Induced Keratouveitis: A Case Report.
Kirk J, Gunn D, Wong N, Minchin E, Darcy K
Cornea 2020 May;39(5):654-656. doi: 10.1097/ICO.0000000000002225. PMID: 31842040
External ophthalmomyiasis: a case series and review of ophthalmomyiasis in Turkey.
Özyol P, Özyol E, Sankur F
Int Ophthalmol 2016 Dec;36(6):887-891. Epub 2016 Feb 19 doi: 10.1007/s10792-016-0204-9. PMID: 26895273
Ligneous conjunctivitis in plasminogen-deficient mice.
Drew AF, Kaufman AH, Kombrinck KW, Danton MJ, Daugherty CC, Degen JL, Bugge TH
Blood 1998 Mar 1;91(5):1616-24. PMID: 9473227

Therapy

Haemolacria: a case of pseudomembranous conjunctivitis in a neonate.
Boffa MM, Spiteri A
BMJ Case Rep 2020 Jun 30;13(6) doi: 10.1136/bcr-2020-235110. PMID: 32606124Free PMC Article
Ocular exposure to paraquat resulting in keratopathy, pseudomembranous conjunctivitis and symblepharon.
LaHood BR, Avery N, Covello A, Allbon D
N Z Med J 2017 Jun 2;130(1456):83-85. PMID: 28571054
Plasmapheresis, Intravenous Immunoglobulins, and Autologous Serum Eyedrops in the Acute Eye Complications of Toxic Epidermal Necrolysis.
Pinna A, Nuvoli E, Blasetti F, Posadinu MA, Boscia F
Eur J Ophthalmol 2017 Nov 8;27(6):658-663. doi: 10.5301/ejo.5000923. PMID: 28362052
Visual acuity and anterior segment findings in chronic graft-versus-host disease.
Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943
Ocular manifestations of graft versus host disease.
Anderson NG, Regillo C
Curr Opin Ophthalmol 2004 Dec;15(6):503-7. doi: 10.1097/01.icu.0000143684.22362.46. PMID: 15523196

Prognosis

Case for conservative management of adenoviral pseudomembranous conjunctivitis.
Gilmour KM, Ramaesh K
BMJ Case Rep 2023 Feb 21;16(2) doi: 10.1136/bcr-2022-253014. PMID: 36810328Free PMC Article
Bristle Worm-Induced Keratouveitis: A Case Report.
Kirk J, Gunn D, Wong N, Minchin E, Darcy K
Cornea 2020 May;39(5):654-656. doi: 10.1097/ICO.0000000000002225. PMID: 31842040
Conjunctival Acute Graft-versus-Host Disease in Adult Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation: A Cohort Study.
Liu YC, Gau JP, Lin PY, Liu CJ, Liu CJ, Liu JH, Fan NW
PLoS One 2016;11(11):e0167129. Epub 2016 Nov 30 doi: 10.1371/journal.pone.0167129. PMID: 27902756Free PMC Article
Visual acuity and anterior segment findings in chronic graft-versus-host disease.
Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943
Successful treatment of Stevens-Johnson syndrome with steroid pulse therapy at disease onset.
Araki Y, Sotozono C, Inatomi T, Ueta M, Yokoi N, Ueda E, Kishimoto S, Kinoshita S
Am J Ophthalmol 2009 Jun;147(6):1004-11, 1011.e1. Epub 2009 Mar 14 doi: 10.1016/j.ajo.2008.12.040. PMID: 19285657

Clinical prediction guides

Pseudomembranous conjunctivitis with hand, foot and mouth disease in a pregnant woman : a case report.
Kim YJ, Kim TG
BMC Ophthalmol 2021 Mar 2;21(1):113. doi: 10.1186/s12886-021-01878-7. PMID: 33653308Free PMC Article
Epidemiology of pseudomembranous conjunctivitis in a tertiary hospital: A 2-year retrospective study.
de-Arriba-Palomero F, Salvá-Palomeque T, de-Arriba-Palomero P, Arnalich-Montiel F
Eur J Ophthalmol 2021 Sep;31(5):2275-2279. Epub 2020 Sep 9 doi: 10.1177/1120672120957581. PMID: 32907398
Plasmapheresis, Intravenous Immunoglobulins, and Autologous Serum Eyedrops in the Acute Eye Complications of Toxic Epidermal Necrolysis.
Pinna A, Nuvoli E, Blasetti F, Posadinu MA, Boscia F
Eur J Ophthalmol 2017 Nov 8;27(6):658-663. doi: 10.5301/ejo.5000923. PMID: 28362052
Visual acuity and anterior segment findings in chronic graft-versus-host disease.
Allan EJ, Flowers ME, Lin MP, Bensinger RE, Martin PJ, Wu MC
Cornea 2011 Dec;30(12):1392-7. doi: 10.1097/ICO.0b013e31820ce6d0. PMID: 21996943
Ligneous conjunctivitis in plasminogen-deficient mice.
Drew AF, Kaufman AH, Kombrinck KW, Danton MJ, Daugherty CC, Degen JL, Bugge TH
Blood 1998 Mar 1;91(5):1616-24. PMID: 9473227

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