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Anisakiasis

MedGen UID:
102418
•Concept ID:
C0162576
•
Disease or Syndrome
Synonyms: Anisakis infection; Pseudoterranova infection
SNOMED CT: Anisakiasis (442652006); Infection by Anisakis larva (442652006); Infection caused by Anisakis larva (442652006)
 
Monarch Initiative: MONDO:0015200
Orphanet: ORPHA1070

Definition

A fish-borne zoonosis caused by the ingestion of third stage larvae of nematodes belonging to the genus <i>Anisakis</i>, present in fish or cephalopods. Following its penetration in the human gastrointestinal tract, the parasite can cause gastrointestinal classified as acute (manifesting as abdominal pain, diarrhea, nausea and vomiting), chronic, or ectopic reactions or allergic manifestations (urticaria, angioedema, anaphylactic shock). [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnisakiasis

Professional guidelines

PubMed

Biology, Epidemiology, Clinical Features, Diagnosis, and Treatment of Selected Fish-borne Parasitic Zoonoses.
Cong W, Elsheikha HM
Yale J Biol Med 2021 Jun;94(2):297-309. Epub 2021 Jun 30 PMID: 34211350Free PMC Article
Diagnosis and treatment of common intestinal helminths. II: Common intestinal nematodes.
Tanowitz HB, Weiss LM, Wittner M
Gastroenterologist 1994 Mar;2(1):39-49. PMID: 8055230
Modern techniques in the diagnosis and treatment of gastrointestinal and biliary tree parasites.
el Sheikh Mohamed AR, al Karawi MA, Yasawy MI
Hepatogastroenterology 1991 Apr;38(2):180-8. PMID: 1855776

Recent clinical studies

Etiology

IgE-mediated Anisakis allergy in children.
Pontone M, Giovannini M, Barni S, Mori F, Venturini E, Galli L, Valleriani C, Vecillas LL, Sackesen C, Lopata AL, Buyuktiryaki B
Allergol Immunopathol (Madr) 2023;51(1):98-109. Epub 2023 Jan 1 doi: 10.15586/aei.v51i1.692. PMID: 36617828
Parasites in Food: From a Neglected Position to an Emerging Issue.
Robertson LJ
Adv Food Nutr Res 2018;86:71-113. Epub 2018 May 7 doi: 10.1016/bs.afnr.2018.04.003. PMID: 30077225Free PMC Article
Parasite allergens.
Caraballo L, Coronado S
Mol Immunol 2018 Aug;100:113-119. Epub 2018 Mar 24 doi: 10.1016/j.molimm.2018.03.014. PMID: 29588070
Seafood Allergy, Toxicity, and Intolerance: A Review.
Prester L
J Am Coll Nutr 2016;35(3):271-83. Epub 2015 Aug 7 doi: 10.1080/07315724.2015.1014120. PMID: 26252073
Foodborne anisakiasis and allergy.
Baird FJ, Gasser RB, Jabbar A, Lopata AL
Mol Cell Probes 2014 Aug;28(4):167-74. Epub 2014 Feb 27 doi: 10.1016/j.mcp.2014.02.003. PMID: 24583228

Diagnosis

Anisakiasis: Imaging findings.
Fornell Pérez R, Urizar Gorosarri M, Pérez Bea M
Radiologia (Engl Ed) 2022 May-Jun;64(3):245-255. doi: 10.1016/j.rxeng.2022.05.001. PMID: 35676056
Histamine and Scombrotoxins.
Hungerford JM
Toxicon 2021 Oct 15;201:115-126. Epub 2021 Aug 20 doi: 10.1016/j.toxicon.2021.08.013. PMID: 34419509
Anisakiasis and Anisakis: An underdiagnosed emerging disease and its main etiological agents.
Adroher-Auroux FJ, Benítez-Rodríguez R
Res Vet Sci 2020 Oct;132:535-545. Epub 2020 Aug 6 doi: 10.1016/j.rvsc.2020.08.003. PMID: 32828066
Parasite allergens.
Caraballo L, Coronado S
Mol Immunol 2018 Aug;100:113-119. Epub 2018 Mar 24 doi: 10.1016/j.molimm.2018.03.014. PMID: 29588070
Anisakiasis.
Sakanari JA, McKerrow JH
Clin Microbiol Rev 1989 Jul;2(3):278-84. doi: 10.1128/CMR.2.3.278. PMID: 2670191Free PMC Article

Therapy

Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update.
Chai JY, Jung BK, Hong SJ
Korean J Parasitol 2021 Jun;59(3):189-225. Epub 2021 Jun 21 doi: 10.3347/kjp.2021.59.3.189. PMID: 34218593Free PMC Article
Gastro-allergic anisakiasis: The first case reported in Colombia and a literature review.
Patiño JA, Olivera MJ
Biomedica 2019 Jun 15;39(2):241-246. doi: 10.7705/biomedica.v39i2.3936. PMID: 31529811
Common Symptoms from an Uncommon Infection: Gastrointestinal Anisakiasis.
Shimamura Y, Muwanwella N, Chandran S, Kandel G, Marcon N
Can J Gastroenterol Hepatol 2016;2016:5176502. Epub 2016 Oct 9 doi: 10.1155/2016/5176502. PMID: 27800471Free PMC Article
Fish Parasites: A Growing Concern During Pregnancy.
Villazanakretzer DL, Napolitano PG, Cummings KF, Magann EF
Obstet Gynecol Surv 2016 Apr;71(4):253-9. doi: 10.1097/OGX.0000000000000303. PMID: 27065071
Intestinal parasitic infection.
Park MS, Kim KW, Ha HK, Lee DH
Abdom Imaging 2008 Mar-Apr;33(2):166-71. doi: 10.1007/s00261-007-9324-z. PMID: 17901912

Prognosis

Anisakiasis Annual Incidence and Causative Species, Japan, 2018-2019.
Sugiyama H, Shiroyama M, Yamamoto I, Ishikawa T, Morishima Y
Emerg Infect Dis 2022 Oct;28(10):2105-2108. doi: 10.3201/eid2810.220627. PMID: 36148963Free PMC Article
An Overview of Fish-borne Nematodiases among Returned Travelers for Recent 25 Years- Unexpected Diseases Sometimes Far Away from the Origin.
Eiras JC, Pavanelli GC, Takemoto RM, Nawa Y
Korean J Parasitol 2018 Jun;56(3):215-227. Epub 2018 Jun 30 doi: 10.3347/kjp.2018.56.3.215. PMID: 29996625Free PMC Article
Distinguishing gastric anisakiasis from non-anisakiasis using unenhanced computed tomography.
Ashida H, Igarashi T, Morikawa K, Motohashi K, Fukuda K, Tamai N
Abdom Radiol (NY) 2017 Dec;42(12):2792-2798. doi: 10.1007/s00261-017-1214-4. PMID: 28643138
Haemoglobin, a new major allergen of Anisakis simplex.
González-Fernández J, Daschner A, Nieuwenhuizen NE, Lopata AL, Frutos CD, Valls A, Cuéllar C
Int J Parasitol 2015 May;45(6):399-407. Epub 2015 Feb 12 doi: 10.1016/j.ijpara.2015.01.002. PMID: 25683373
Parasitic infections of the pleural space.
Roberts PP
Semin Respir Infect 1988 Dec;3(4):362-82. PMID: 3062728

Clinical prediction guides

Anisakis spp. as etiological agent of zoonotic disease and allergy in European region – an overview.
Morozińska-Gogol J
Ann Parasitol 2019;65(4):303-314. doi: 10.17420/ap6504.214. PMID: 32191412
Parasite allergens.
Caraballo L, Coronado S
Mol Immunol 2018 Aug;100:113-119. Epub 2018 Mar 24 doi: 10.1016/j.molimm.2018.03.014. PMID: 29588070
Distinguishing gastric anisakiasis from non-anisakiasis using unenhanced computed tomography.
Ashida H, Igarashi T, Morikawa K, Motohashi K, Fukuda K, Tamai N
Abdom Radiol (NY) 2017 Dec;42(12):2792-2798. doi: 10.1007/s00261-017-1214-4. PMID: 28643138
Acute invasive small-bowel Anisakiasis: clinical and CT findings in 19 patients.
Lee JS, Kim BS, Kim SH, Park JK, Choi G, Hwang IK, Jeong SY, Hyun CL, Song HJ, Chung YB
Abdom Imaging 2014 Jun;39(3):452-8. doi: 10.1007/s00261-014-0106-0. PMID: 24562690
Anisakis--a food-borne parasite that triggers allergic host defences.
Nieuwenhuizen NE, Lopata AL
Int J Parasitol 2013 Nov;43(12-13):1047-57. Epub 2013 Aug 27 doi: 10.1016/j.ijpara.2013.08.001. PMID: 23994604

Recent systematic reviews

World-wide prevalence of Anisakis larvae in fish and its relationship to human allergic anisakiasis: a systematic review.
Rahmati AR, Kiani B, Afshari A, Moghaddas E, Williams M, Shamsi S
Parasitol Res 2020 Nov;119(11):3585-3594. Epub 2020 Oct 6 doi: 10.1007/s00436-020-06892-0. PMID: 33025215
Anisakis sensitization in different population groups and public health impact: A systematic review.
Mazzucco W, Raia DD, Marotta C, Costa A, Ferrantelli V, Vitale F, Casuccio A
PLoS One 2018;13(9):e0203671. Epub 2018 Sep 20 doi: 10.1371/journal.pone.0203671. PMID: 30235242Free PMC Article
Prevalence and Mean Intensity of Anisakidae Parasite in Seafood Caught in the Mediterranean Sea Focusing on Fish Species at Risk of Being Raw-consumed. A Meta Analysis and Systematic Review.
Colombo F, Cattaneo P, Castelletti M, Bernardi C
Crit Rev Food Sci Nutr 2016 Jul 3;56(9):1405-16. doi: 10.1080/10408398.2012.755947. PMID: 25807208

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