U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cancrum oris

MedGen UID:
10366
Concept ID:
C0028271
Disease or Syndrome
Synonyms: Noma; Noma neonatorum; Oral gangrene; Oro-facial gangrene; Oro-facial noma
SNOMED CT: Cancrum oris (18116006); Gangrenous stomatitis (18116006); Noma (18116006); Acute gangrenous stomatitis (18116006)
 
Monarch Initiative: MONDO:0017124
Orphanet: ORPHA2700

Definition

Noma is a gangrenous disease that causes severe destruction of the soft and osseous tissues of the face. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCancrum oris
Follow this link to review classifications for Cancrum oris in Orphanet.

Professional guidelines

PubMed

Rüegg EM, Baratti-Mayer D, Jaquinet A, Montandon D, Pittet-Cuénod B
Int J Oral Maxillofac Surg 2018 Dec;47(12):1527-1533. Epub 2018 Aug 10 doi: 10.1016/j.ijom.2018.07.012. PMID: 30104131
SHRAND H
Clin Proc 1947 Jul;6(5):197-203. PMID: 20261264
SHIRCORE JO
East Afr Med J 1947 May;24(5):202. PMID: 20255595

Recent clinical studies

Etiology

Farley E, Amirtharajah M, Shaye DA
Curr Opin Otolaryngol Head Neck Surg 2022 Aug 1;30(4):219-225. Epub 2022 Jul 5 doi: 10.1097/MOO.0000000000000819. PMID: 35906973
Farley E, Mehta U, Srour ML, Lenglet A
PLoS Negl Trop Dis 2021 Dec;15(12):e0009844. Epub 2021 Dec 14 doi: 10.1371/journal.pntd.0009844. PMID: 34905547Free PMC Article
Shaye DA, Winters R, Rabbels J, Adentunji AS, Magee A, Vo D
Laryngoscope 2019 Jan;129(1):96-99. Epub 2018 Sep 8 doi: 10.1002/lary.27230. PMID: 30194753
Feller L, Altini M, Chandran R, Khammissa RA, Masipa JN, Mohamed A, Lemmer J
J Oral Pathol Med 2014 Jan;43(1):1-6. Epub 2013 May 4 doi: 10.1111/jop.12079. PMID: 23647162
Enwonwu CO, Falkler WA Jr, Idigbe EO, Savage KO
Oral Dis 1999 Apr;5(2):144-9. doi: 10.1111/j.1601-0825.1999.tb00080.x. PMID: 10522212

Diagnosis

Farley E, Amirtharajah M, Shaye DA
Curr Opin Otolaryngol Head Neck Surg 2022 Aug 1;30(4):219-225. Epub 2022 Jul 5 doi: 10.1097/MOO.0000000000000819. PMID: 35906973
Galli A, Brugger C, Fürst T, Monnier N, Winkler MS, Steinmann P
Lancet Infect Dis 2022 Aug;22(8):e221-e230. Epub 2022 Mar 15 doi: 10.1016/S1473-3099(21)00698-8. PMID: 35303478
Adeniyi SA, Awosan KJ
Ann Afr Med 2019 Jan-Mar;18(1):17-22. doi: 10.4103/aam.aam_5_18. PMID: 30729928Free PMC Article
Dahlén G, Ebenfelt A
Expert Rev Anti Infect Ther 2011 Feb;9(2):227-36. doi: 10.1586/eri.10.172. PMID: 21342070
Adolph HP, Yugueros P, Woods JE
Ann Plast Surg 1996 Dec;37(6):657-68. doi: 10.1097/00000637-199612000-00017. PMID: 8988783

Therapy

Crecelius EM, Burnett MW
J Spec Oper Med 2020 Summer;20(2):136-138. doi: 10.55460/3NFC-341T. PMID: 32573751
Feller L, Altini M, Chandran R, Khammissa RA, Masipa JN, Mohamed A, Lemmer J
J Oral Pathol Med 2014 Jan;43(1):1-6. Epub 2013 May 4 doi: 10.1111/jop.12079. PMID: 23647162
Dahlén G, Ebenfelt A
Expert Rev Anti Infect Ther 2011 Feb;9(2):227-36. doi: 10.1586/eri.10.172. PMID: 21342070
Nash ES, Cheng LH, Smart K
Br J Oral Maxillofac Surg 1991 Feb;29(1):51-3. doi: 10.1016/0266-4356(91)90176-6. PMID: 1900721
Tempest MN
Br J Surg 1966 Nov;53(11):949-69. doi: 10.1002/bjs.1800531109. PMID: 5331894

Prognosis

Galli A, Brugger C, Fürst T, Monnier N, Winkler MS, Steinmann P
Lancet Infect Dis 2022 Aug;22(8):e221-e230. Epub 2022 Mar 15 doi: 10.1016/S1473-3099(21)00698-8. PMID: 35303478
Farley E, Mehta U, Srour ML, Lenglet A
PLoS Negl Trop Dis 2021 Dec;15(12):e0009844. Epub 2021 Dec 14 doi: 10.1371/journal.pntd.0009844. PMID: 34905547Free PMC Article
Ashok N, Tarakji B, Darwish S, Rodrigues JC, Altamimi MA
Glob J Health Sci 2015 Jul 30;8(4):53-9. doi: 10.5539/gjhs.v8n4p53. PMID: 26573028Free PMC Article
Enwonwu CO, Falkler WA Jr, Idigbe EO, Savage KO
Oral Dis 1999 Apr;5(2):144-9. doi: 10.1111/j.1601-0825.1999.tb00080.x. PMID: 10522212
Adolph HP, Yugueros P, Woods JE
Ann Plast Surg 1996 Dec;37(6):657-68. doi: 10.1097/00000637-199612000-00017. PMID: 8988783

Clinical prediction guides

Gebretsadik HG, de Kiev LC
PLoS Negl Trop Dis 2022 Sep;16(9):e0010372. Epub 2022 Sep 13 doi: 10.1371/journal.pntd.0010372. PMID: 36099293Free PMC Article
Feller L, Khammissa RAG, Altini M, Lemmer J
Periodontol 2000 2019 Jun;80(1):189-199. doi: 10.1111/prd.12275. PMID: 31090145Free PMC Article
Falkler WA Jr, Enwonwu CO, Idigbe EO
Oral Dis 1999 Apr;5(2):150-5. doi: 10.1111/j.1601-0825.1999.tb00081.x. PMID: 10522213
Falkler WA Jr, Enwonwu CO, Idigbe EO
Am J Trop Med Hyg 1999 Jan;60(1):150-6. doi: 10.4269/ajtmh.1999.60.150. PMID: 9988340
Enwonwu CO
Bull World Health Organ 1995;73(4):541-5. PMID: 7554028Free PMC Article

Recent systematic reviews

Onu JU, Aluh DO, Ononiwu CN
Trop Doct 2023 Oct;53(4):470-474. Epub 2023 May 10 doi: 10.1177/00494755231175529. PMID: 37165663
Galli A, Brugger C, Fürst T, Monnier N, Winkler MS, Steinmann P
Lancet Infect Dis 2022 Aug;22(8):e221-e230. Epub 2022 Mar 15 doi: 10.1016/S1473-3099(21)00698-8. PMID: 35303478

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...