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Basal Cell Adenoma

MedGen UID:
104696
Concept ID:
C0205646
Neoplastic Process
Synonyms: Adenoma, Basal Cell; Adenomas, Basal Cell; Basal Cell Adenomas
SNOMED CT: Basal cell adenoma (27230006)

Definition

A salivary gland benign epithelial neoplasm with a uniform, monomorphic appearance that is dominated by basal cells forming trabecular structures. It is rare and occurs mostly on the parotid gland. The average age of patients has been reported to be 58 years. Swelling is the most constant clinical finding. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBasal Cell Adenoma

Professional guidelines

PubMed

Rzepakowska A, Osuch-Wójcikiewicz E, Sobol M, Cruz R, Sielska-Badurek E, Niemczyk K
Eur Arch Otorhinolaryngol 2017 Aug;274(8):3231-3240. Epub 2017 Jun 13 doi: 10.1007/s00405-017-4636-2. PMID: 28612315Free PMC Article
Seifert G
Semin Diagn Pathol 1996 May;13(2):95-103. PMID: 8734415
Nishimura T, Furukawa M, Kawahara E, Miwa A
J Laryngol Otol 1991 Dec;105(12):1057-60. doi: 10.1017/s0022215100118183. PMID: 1664847

Recent clinical studies

Etiology

Bianchini C, Brugali M, Migliorelli A, Corazzi V, Cammaroto G, Meccariello G, Stomeo F, Ciorba A, Pelucchi S
Minerva Surg 2023 Dec;78(6):626-632. Epub 2023 Aug 2 doi: 10.23736/S2724-5691.23.09876-3. PMID: 37530711
Terada T, Kawata R, Higashino M, Kurisu Y, Kuwabara H, Hirose Y
Auris Nasus Larynx 2021 Apr;48(2):310-316. Epub 2020 Sep 17 doi: 10.1016/j.anl.2020.08.024. PMID: 32950324
Hellquist H, Paiva-Correia A, Vander Poorten V, Quer M, Hernandez-Prera JC, Andreasen S, Zbären P, Skalova A, Rinaldo A, Ferlito A
Adv Ther 2019 Aug;36(8):1950-1974. Epub 2019 Jun 17 doi: 10.1007/s12325-019-01007-3. PMID: 31209701Free PMC Article
Wu TT, Bao YY, Zhou SH, Wang QY, Shen LF
Medicine (Baltimore) 2018 Aug;97(34):e11837. doi: 10.1097/MD.0000000000011837. PMID: 30142775Free PMC Article
Mukai H, Motoori K, Horikoshi T, Takishima H, Nagai Y, Okamoto Y, Uno T
Dentomaxillofac Radiol 2016;45(4):20150322. Epub 2016 Feb 3 doi: 10.1259/dmfr.20150322. PMID: 26837669Free PMC Article

Diagnosis

Rito M, Esteves S, Fonseca I
Head Neck Pathol 2022 Dec;16(4):1157-1166. Epub 2022 Aug 10 doi: 10.1007/s12105-022-01484-z. PMID: 35947346Free PMC Article
Robinson RA
Surg Pathol Clin 2021 Mar;14(1):25-42. Epub 2021 Jan 5 doi: 10.1016/j.path.2020.09.005. PMID: 33526221
Amalanathan S , Kumar CS , Sinhasan SP
Kathmandu Univ Med J (KUMJ) 2020 Oct.-Dec.;18(72):434-436. PMID: 34165108
Seethala RR
Mod Pathol 2017 Jan;30(s1):S84-S95. doi: 10.1038/modpathol.2016.190. PMID: 28060371
Witt RL, Nicolai P
Adv Otorhinolaryngol 2016;78:63-70. Epub 2016 Apr 12 doi: 10.1159/000442126. PMID: 27093568

Therapy

Hu Y, Zheng C, Cao R, Hong W, Zhang Z
J Int Med Res 2020 Jan;48(1):300060519892783. doi: 10.1177/0300060519892783. PMID: 31971033Free PMC Article
Lee JY, Kim HJ, Kim YK, Cha J, Kim ST
Diagn Interv Radiol 2019 Jul;25(4):285-290. doi: 10.5152/dir.2019.18337. PMID: 31120425Free PMC Article
Wu TT, Bao YY, Zhou SH, Wang QY, Shen LF
Medicine (Baltimore) 2018 Aug;97(34):e11837. doi: 10.1097/MD.0000000000011837. PMID: 30142775Free PMC Article
Yerli H, Aydin E, Coskun M, Geyik E, Ozluoglu LN, Haberal N, Kaskati T
J Comput Assist Tomogr 2007 Mar-Apr;31(2):309-16. doi: 10.1097/01.rct.0000236418.82395.b3. PMID: 17414771
Lee DK, Chung KW, Baek CH, Jeong HS, Ko YH, Son YI
J Comput Assist Tomogr 2005 Nov-Dec;29(6):884-8. doi: 10.1097/01.rct.0000183273.70422.c4. PMID: 16272868

Prognosis

Rito M, Esteves S, Fonseca I
Head Neck Pathol 2022 Dec;16(4):1157-1166. Epub 2022 Aug 10 doi: 10.1007/s12105-022-01484-z. PMID: 35947346Free PMC Article
Robinson RA
Surg Pathol Clin 2021 Mar;14(1):25-42. Epub 2021 Jan 5 doi: 10.1016/j.path.2020.09.005. PMID: 33526221
Terada T, Kawata R, Higashino M, Kurisu Y, Kuwabara H, Hirose Y
Auris Nasus Larynx 2021 Apr;48(2):310-316. Epub 2020 Sep 17 doi: 10.1016/j.anl.2020.08.024. PMID: 32950324
Amalanathan S , Kumar CS , Sinhasan SP
Kathmandu Univ Med J (KUMJ) 2020 Oct.-Dec.;18(72):434-436. PMID: 34165108
Witt RL, Nicolai P
Adv Otorhinolaryngol 2016;78:63-70. Epub 2016 Apr 12 doi: 10.1159/000442126. PMID: 27093568

Clinical prediction guides

Bianchini C, Brugali M, Migliorelli A, Corazzi V, Cammaroto G, Meccariello G, Stomeo F, Ciorba A, Pelucchi S
Minerva Surg 2023 Dec;78(6):626-632. Epub 2023 Aug 2 doi: 10.23736/S2724-5691.23.09876-3. PMID: 37530711
Shinmura K, Kusafuka K, Kawasaki H, Kato H, Hariyama T, Tsuchiya K, Kawanishi Y, Funai K, Misawa K, Mineta H, Sugimura H
J Pathol 2021 Aug;254(5):519-530. Epub 2021 May 29 doi: 10.1002/path.5688. PMID: 33931860
Terada T, Kawata R, Higashino M, Kurisu Y, Kuwabara H, Hirose Y
Auris Nasus Larynx 2021 Apr;48(2):310-316. Epub 2020 Sep 17 doi: 10.1016/j.anl.2020.08.024. PMID: 32950324
Hellquist H, Paiva-Correia A, Vander Poorten V, Quer M, Hernandez-Prera JC, Andreasen S, Zbären P, Skalova A, Rinaldo A, Ferlito A
Adv Ther 2019 Aug;36(8):1950-1974. Epub 2019 Jun 17 doi: 10.1007/s12325-019-01007-3. PMID: 31209701Free PMC Article
Witt RL, Nicolai P
Adv Otorhinolaryngol 2016;78:63-70. Epub 2016 Apr 12 doi: 10.1159/000442126. PMID: 27093568

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