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Giant Cell Carcinoma

MedGen UID:
104920
Concept ID:
C0206703
Neoplastic Process
Synonyms: Carcinoma, Giant Cell; Carcinomas, Giant Cell; Cell Carcinoma, Giant; Cell Carcinomas, Giant; Giant Cell Carcinomas
SNOMED CT: Giant cell carcinoma (42596004)

Definition

A malignant epithelial neoplasm composed of giant, pleomorphic cells. [from NCI]

Professional guidelines

PubMed

Ueberroth BE, Liu AJ, Graham RP, Bekaii-Saab TS, McWilliams RR, Mahipal A, Truty MJ, Mody K, Sonbol MB, Halfdanarson TR
Pancreas 2021 Aug 1;50(7):952-956. doi: 10.1097/MPA.0000000000001858. PMID: 34369897
Nilsson O, Lindeberg J, Zedenius J, Ekman E, Tennvall J, Blomgren H, Grimelius L, Lundell G, Wallin G
World J Surg 1998 Jul;22(7):725-30. doi: 10.1007/s002689900460. PMID: 9606289
Jereb B, Stjernswärd J, Löwhagen T
Cancer 1975 May;35(5):1293-5. doi: 10.1002/1097-0142(197505)35:5<1293::aid-cncr2820350504>3.0.co;2-w. PMID: 1122480

Recent clinical studies

Etiology

Bilé-Silva A, Lopez-Beltran A, Rasteiro H, Vau N, Blanca A, Gomez E, Gaspar F, Cheng L
Virchows Arch 2023 Mar;482(3):493-505. Epub 2023 Jan 5 doi: 10.1007/s00428-022-03481-7. PMID: 36600115Free PMC Article
Ueberroth BE, Liu AJ, Graham RP, Bekaii-Saab TS, McWilliams RR, Mahipal A, Truty MJ, Mody K, Sonbol MB, Halfdanarson TR
Pancreas 2021 Aug 1;50(7):952-956. doi: 10.1097/MPA.0000000000001858. PMID: 34369897
Mikuz G
Anal Quant Cytopathol Histpathol 2015 Feb;37(1):39-47. PMID: 26072633
Humphrey PA
Histopathology 2012 Jan;60(1):59-74. doi: 10.1111/j.1365-2559.2011.04039.x. PMID: 22212078
Pelosi G, Sonzogni A, De Pas T, Galetta D, Veronesi G, Spaggiari L, Manzotti M, Fumagalli C, Bresaola E, Nappi O, Viale G, Rosai J
Int J Surg Pathol 2010 Apr;18(2):103-20. Epub 2009 Jan 4 doi: 10.1177/1066896908330049. PMID: 19124452

Diagnosis

He J, Ni JP, Li GB, Yao J, Ni B
Clin Respir J 2023 Mar;17(3):197-210. Epub 2023 Jan 31 doi: 10.1111/crj.13586. PMID: 36718941Free PMC Article
Bilé-Silva A, Lopez-Beltran A, Rasteiro H, Vau N, Blanca A, Gomez E, Gaspar F, Cheng L
Virchows Arch 2023 Mar;482(3):493-505. Epub 2023 Jan 5 doi: 10.1007/s00428-022-03481-7. PMID: 36600115Free PMC Article
Agaimy A
Semin Diagn Pathol 2021 Nov;38(6):187-192. Epub 2021 Sep 20 doi: 10.1053/j.semdp.2021.09.003. PMID: 34583859
Smadhi H, Boudaya MS, Abdannadher M, BenAbdelghaffar H, Kamoun H, Ayadi A, Fekih L, Marghli A, Megdiche ML
Tunis Med 2019 Jan;97(1):128-132. PMID: 31535704
Mulligan AM, Plotkin A, Rouzbahman M, Soslow RA, Gilks CB, Clarke BA
Am J Surg Pathol 2010 Aug;34(8):1132-8. doi: 10.1097/PAS.0b013e3181e6579c. PMID: 20588176

Therapy

Bertolin A, Lionello M, Baldovin M, Ghirardo G, Rizzotto G
J Surg Oncol 2022 Feb;125(2):145-150. Epub 2021 Sep 20 doi: 10.1002/jso.26675. PMID: 34542917
Forest F, Yvorel V, Karpathiou G, Stachowicz ML, Vergnon JM, Fournel P, Tiffet O, Trombert B, Péoc'h M
Hum Pathol 2016 Mar;49:99-106. Epub 2015 Nov 2 doi: 10.1016/j.humpath.2015.10.006. PMID: 26826416
Alexiev BA, Papadimitriou JC, Chai TC, Ramos E, Staats PN, Drachenberg CB
Pathol Res Pract 2013 Apr;209(4):255-9. Epub 2013 Mar 6 doi: 10.1016/j.prp.2013.01.008. PMID: 23481349
Wallin G, Lundell G, Tennvall J
Scand J Surg 2004;93(4):272-7. doi: 10.1177/145749690409300404. PMID: 15658667
Davidson JF, McNicol GP, Frank GL, Anderson TJ, Douglas AS
Br Med J 1969 Jan 11;1(5636):88-91. doi: 10.1136/bmj.1.5636.88. PMID: 5761832Free PMC Article

Prognosis

He J, Ni JP, Li GB, Yao J, Ni B
Clin Respir J 2023 Mar;17(3):197-210. Epub 2023 Jan 31 doi: 10.1111/crj.13586. PMID: 36718941Free PMC Article
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316
Mikuz G
Anal Quant Cytopathol Histpathol 2015 Feb;37(1):39-47. PMID: 26072633
Travis WD
Arch Pathol Lab Med 2010 Nov;134(11):1645-58. doi: 10.5858/2010-0086-RAR.1. PMID: 21043818
Mulligan AM, Plotkin A, Rouzbahman M, Soslow RA, Gilks CB, Clarke BA
Am J Surg Pathol 2010 Aug;34(8):1132-8. doi: 10.1097/PAS.0b013e3181e6579c. PMID: 20588176

Clinical prediction guides

He J, Ni JP, Li GB, Yao J, Ni B
Clin Respir J 2023 Mar;17(3):197-210. Epub 2023 Jan 31 doi: 10.1111/crj.13586. PMID: 36718941Free PMC Article
Bilé-Silva A, Lopez-Beltran A, Rasteiro H, Vau N, Blanca A, Gomez E, Gaspar F, Cheng L
Virchows Arch 2023 Mar;482(3):493-505. Epub 2023 Jan 5 doi: 10.1007/s00428-022-03481-7. PMID: 36600115Free PMC Article
Sak SD
Turk Patoloji Derg 2015;31 Suppl 1:34-47. doi: 10.5146/tjpath.2015.01313. PMID: 26177316
Mikuz G
Anal Quant Cytopathol Histpathol 2015 Feb;37(1):39-47. PMID: 26072633
Mulligan AM, Plotkin A, Rouzbahman M, Soslow RA, Gilks CB, Clarke BA
Am J Surg Pathol 2010 Aug;34(8):1132-8. doi: 10.1097/PAS.0b013e3181e6579c. PMID: 20588176

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