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Central neurocytoma

MedGen UID:
104924
Concept ID:
C0206719
Neoplastic Process
Synonyms: Central Neurocytoma; Central Neurocytomas; Neurocytoma, Central; Neurocytomas, Central
SNOMED CT: Central neurocytoma - histology (128858006); Neurolipocytoma (128858006); Medullocytoma (128858006); Lipomatous medulloblastoma (128858006); Central neurocytoma (128858006)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0019134
Orphanet: ORPHA73256

Definition

Central neurocytoma is a very rare brain tumor of young adults (over 100 cases reported worldwide). It is typically found in the lateral ventricles and occasionally in the third ventricle. Symptoms are those of increased intracranial pressure: headache, nausea and vomiting, drowsiness, vision problems and mental changes. Total removal of the tumor is the therapy of choice. Post-operative prognosis is generally good. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral neurocytoma
Follow this link to review classifications for Central neurocytoma in Orphanet.

Professional guidelines

PubMed

Steinsiepe VK, Frick H, Jochum W, Fournier JY
J Neurol Surg A Cent Eur Neurosurg 2021 Nov;82(6):599-603. Epub 2020 Dec 22 doi: 10.1055/s-0040-1718693. PMID: 33352608
Johnson MO, Kirkpatrick JP, Patel MP, Desjardins A, Randazzo DM, Friedman HS, Ashley DM, Peters KB
CNS Oncol 2019 Nov 1;8(3):CNS41. Epub 2019 Nov 5 doi: 10.2217/cns-2019-0012. PMID: 31686534Free PMC Article
Monaco EA 3rd, Niranjan A, Lunsford LD
Neurosurg Clin N Am 2015 Jan;26(1):37-44. Epub 2014 Oct 18 doi: 10.1016/j.nec.2014.09.008. PMID: 25432182

Recent clinical studies

Etiology

AbdelBari Mattar M, Shebl AM, Toson EA
World Neurosurg 2021 Feb;146:e184-e193. Epub 2020 Oct 19 doi: 10.1016/j.wneu.2020.10.068. PMID: 33091649
Dutta SW, Kaleem TA, Muller DA, Peterson J, Harrell AC, Quinones-Hinojosa A, Trifiletti DM
J Clin Neurosci 2018 Jul;53:106-111. Epub 2018 Apr 20 doi: 10.1016/j.jocn.2018.04.015. PMID: 29685410
Karthigeyan M, Gupta K, Salunke P
J Child Neurol 2017 Jan;32(1):53-59. Epub 2016 Sep 29 doi: 10.1177/0883073816668994. PMID: 27664193
Thawani JP, Lee JY
Neurosurg Clin N Am 2015 Jan;26(1):67-81. doi: 10.1016/j.nec.2014.09.002. PMID: 25432185
Chen H, Zhou R, Liu J, Tang J
J Clin Neurosci 2012 Jun;19(6):849-53. Epub 2012 Apr 25 doi: 10.1016/j.jocn.2011.06.038. PMID: 22537657

Diagnosis

Steinsiepe VK, Frick H, Jochum W, Fournier JY
J Neurol Surg A Cent Eur Neurosurg 2021 Nov;82(6):599-603. Epub 2020 Dec 22 doi: 10.1055/s-0040-1718693. PMID: 33352608
Muly S, Liu S, Lee R, Nicolaou S, Rojas R, Khosa F
Clin Imaging 2018 Nov-Dec;52:226-239. Epub 2018 Aug 1 doi: 10.1016/j.clinimag.2018.07.021. PMID: 30138862
Bonney PA, Boettcher LB, Krysiak RS 3rd, Fung KM, Sughrue ME
Neurosurg Clin N Am 2015 Jan;26(1):21-9. doi: 10.1016/j.nec.2014.09.001. PMID: 25432180
Yang I, Ung N, Chung LK, Nagasawa DT, Thill K, Park J, Tenn S
Neurosurg Clin N Am 2015 Jan;26(1):5-10. doi: 10.1016/j.nec.2014.09.011. PMID: 25432178
Chen H, Zhou R, Liu J, Tang J
J Clin Neurosci 2012 Jun;19(6):849-53. Epub 2012 Apr 25 doi: 10.1016/j.jocn.2011.06.038. PMID: 22537657

Therapy

Spina A, Garbin E, Albano L, Bisoglio A, Boari N, Mortini P
Neurosurg Rev 2024 Jan 24;47(1):64. doi: 10.1007/s10143-024-02301-7. PMID: 38265530
Johnson MO, Kirkpatrick JP, Patel MP, Desjardins A, Randazzo DM, Friedman HS, Ashley DM, Peters KB
CNS Oncol 2019 Nov 1;8(3):CNS41. Epub 2019 Nov 5 doi: 10.2217/cns-2019-0012. PMID: 31686534Free PMC Article
Dutta SW, Kaleem TA, Muller DA, Peterson J, Harrell AC, Quinones-Hinojosa A, Trifiletti DM
J Clin Neurosci 2018 Jul;53:106-111. Epub 2018 Apr 20 doi: 10.1016/j.jocn.2018.04.015. PMID: 29685410
Patel DM, Schmidt RF, Liu JK
J Clin Neurosci 2013 Sep;20(9):1193-9. Epub 2013 Jun 27 doi: 10.1016/j.jocn.2013.01.001. PMID: 23810386
Park HK, Steven D C
J Neurooncol 2012 May;108(1):115-21. doi: 10.1007/s11060-012-0803-x. PMID: 22442020

Prognosis

Karthigeyan M, Gupta K, Salunke P
J Child Neurol 2017 Jan;32(1):53-59. Epub 2016 Sep 29 doi: 10.1177/0883073816668994. PMID: 27664193
Phi JH, Kim DG
Neurosurg Clin N Am 2015 Jan;26(1):105-8. doi: 10.1016/j.nec.2014.09.015. PMID: 25432189
Choudhri O, Razavi SM, Vogel H, Li G
Neurosurg Clin N Am 2015 Jan;26(1):91-8. Epub 2014 Oct 18 doi: 10.1016/j.nec.2014.09.003. PMID: 25432187
Yang I, Ung N, Chung LK, Nagasawa DT, Thill K, Park J, Tenn S
Neurosurg Clin N Am 2015 Jan;26(1):5-10. doi: 10.1016/j.nec.2014.09.011. PMID: 25432178
Tamiya T, Furuta T, Asari S, Nishimoto A
Neurol Med Chir (Tokyo) 1990 Mar;30(3):178-83. doi: 10.2176/nmc.30.178. PMID: 1697045

Clinical prediction guides

Durrani S, Tebha SS, Qamar MA, Nathani KR, Harrison DJ, Aljameey UA, Jarrah R, Shoushtari A, Bydon M
Neurosurg Rev 2023 Feb 14;46(1):57. doi: 10.1007/s10143-023-01960-2. PMID: 36786867
Chong AW, McAdory LE, Low DCY, Lim EJ, Leong NWL, Ho CL
Clin Imaging 2022 Feb;82:38-52. Epub 2021 Oct 29 doi: 10.1016/j.clinimag.2021.10.008. PMID: 34773811
AbdelBari Mattar M, Shebl AM, Toson EA
World Neurosurg 2021 Feb;146:e184-e193. Epub 2020 Oct 19 doi: 10.1016/j.wneu.2020.10.068. PMID: 33091649
Dutta SW, Kaleem TA, Muller DA, Peterson J, Harrell AC, Quinones-Hinojosa A, Trifiletti DM
J Clin Neurosci 2018 Jul;53:106-111. Epub 2018 Apr 20 doi: 10.1016/j.jocn.2018.04.015. PMID: 29685410
Karthigeyan M, Gupta K, Salunke P
J Child Neurol 2017 Jan;32(1):53-59. Epub 2016 Sep 29 doi: 10.1177/0883073816668994. PMID: 27664193

Recent systematic reviews

Spina A, Garbin E, Albano L, Bisoglio A, Boari N, Mortini P
Neurosurg Rev 2024 Jan 24;47(1):64. doi: 10.1007/s10143-024-02301-7. PMID: 38265530
Al-Umran MR, Al-Umran SR, Arab AF, Dababo MA, Alotaibi FA
Neurochirurgie 2021 Nov;67(6):579-586. Epub 2021 Mar 22 doi: 10.1016/j.neuchi.2021.03.004. PMID: 33766564
Mahavadi AK, Patel PM, Kuchakulla M, Shah AH, Eichberg D, Luther EM, Komotar RJ, Ivan ME
World Neurosurg 2020 May;137:e176-e182. Epub 2020 Jan 27 doi: 10.1016/j.wneu.2020.01.114. PMID: 32001392
Garcia RM, Ivan ME, Oh T, Barani I, Parsa AT
Clin Neurol Neurosurg 2014 Feb;117:55-64. Epub 2013 Dec 7 doi: 10.1016/j.clineuro.2013.11.028. PMID: 24438806
Park HK, Steven D C
J Neurooncol 2012 May;108(1):115-21. doi: 10.1007/s11060-012-0803-x. PMID: 22442020

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