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Suppurative otitis media

MedGen UID:
10506
•Concept ID:
C0029888
•
Disease or Syndrome
Synonyms: Otitis Media, Purulent; Otitis Media, Suppurative; Purulent Otitis Media; Suppurative Otitis Media
SNOMED CT: Otitis media with effusion - purulent (38394007); Purulent otitis media (39288006); Suppurative otitis media (39288006)
 
Monarch Initiative: MONDO:0005975

Definition

Inflammation of the middle ear with purulent discharge. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSuppurative otitis media

Professional guidelines

PubMed

Panel 7: Otitis Media: Treatment and Complications.
Schilder AG, Marom T, Bhutta MF, Casselbrant ML, Coates H, Gisselsson-Solén M, Hall AJ, Marchisio P, Ruohola A, Venekamp RP, Mandel EM
Otolaryngol Head Neck Surg 2017 Apr;156(4_suppl):S88-S105. doi: 10.1177/0194599816633697. PMID: 28372534
Current concepts in the pathogenesis and treatment of chronic suppurative otitis media.
Mittal R, Lisi CV, Gerring R, Mittal J, Mathee K, Narasimhan G, Azad RK, Yao Q, Grati M, Yan D, Eshraghi AA, Angeli SI, Telischi FF, Liu XZ
J Med Microbiol 2015 Oct;64(10):1103-1116. Epub 2015 Aug 5 doi: 10.1099/jmm.0.000155. PMID: 26248613Free PMC Article
Evidence-based management of otitis media: a 5S model approach.
Wasson JD, Yung MW
J Laryngol Otol 2015 Feb;129(2):112-9. Epub 2015 Jan 28 doi: 10.1017/S0022215114003363. PMID: 25627708

Recent clinical studies

Etiology

ABO blood type correlates with risk and protective factors for chronic suppurative otitis media.
Wang J, Chen B, Gao Y, Hu J, Chen Z, Zhang Y
Acta Otolaryngol 2023 Aug;143(8):669-674. Epub 2023 Sep 13 doi: 10.1080/00016489.2023.2252031. PMID: 37702578
Relation between otitis media and sensorineural hearing loss: a systematic review.
Elzinga HBE, van Oorschot HD, Stegeman I, Smit AL
BMJ Open 2021 Aug 12;11(8):e050108. doi: 10.1136/bmjopen-2021-050108. PMID: 34385254Free PMC Article
Unsolved problems and new medical approaches to otitis media.
Principi N, Esposito S
Expert Opin Biol Ther 2020 Jul;20(7):741-749. Epub 2020 Apr 20 doi: 10.1080/14712598.2020.1740677. PMID: 32178551
Antibiotics versus topical antiseptics for chronic suppurative otitis media.
Head K, Chong LY, Bhutta MF, Morris PS, Vijayasekaran S, Burton MJ, Schilder AG, Brennan-Jones CG
Cochrane Database Syst Rev 2020 Jan 6;1(1):CD013056. doi: 10.1002/14651858.CD013056.pub2. PMID: 31902139Free PMC Article
Current concepts in the pathogenesis and treatment of chronic suppurative otitis media.
Mittal R, Lisi CV, Gerring R, Mittal J, Mathee K, Narasimhan G, Azad RK, Yao Q, Grati M, Yan D, Eshraghi AA, Angeli SI, Telischi FF, Liu XZ
J Med Microbiol 2015 Oct;64(10):1103-1116. Epub 2015 Aug 5 doi: 10.1099/jmm.0.000155. PMID: 26248613Free PMC Article

Diagnosis

Tuberculous otitis media.
Bakshi SS, Kaipuzha RR
Med Clin (Barc) 2019 May 3;152(9):e53. Epub 2018 Aug 27 doi: 10.1016/j.medcli.2018.06.017. PMID: 30166127
Chronic Ear Disease.
Emmett SD, Kokesh J, Kaylie D
Med Clin North Am 2018 Nov;102(6):1063-1079. Epub 2018 Sep 20 doi: 10.1016/j.mcna.2018.06.008. PMID: 30342609
Panel 1: Epidemiology and Diagnosis.
Homøe P, Kværner K, Casey JR, Damoiseaux RA, van Dongen TM, Gunasekera H, Jensen RG, Kvestad E, Morris PS, Weinreich HM
Otolaryngol Head Neck Surg 2017 Apr;156(4_suppl):S1-S21. doi: 10.1177/0194599816643510. PMID: 28372531
Otitis media.
Cunningham M, Guardiani E, Kim HJ, Brook I
Future Microbiol 2012 Jun;7(6):733-53. doi: 10.2217/fmb.12.38. PMID: 22702527
Revision mastoidectomy.
Nadol JB Jr
Otolaryngol Clin North Am 2006 Aug;39(4):723-40, vi-vii. doi: 10.1016/j.otc.2006.05.003. PMID: 16895781

Therapy

Systemic antibiotics for chronic suppurative otitis media.
Chong LY, Head K, Webster KE, Dew J, Richmond P, Snelling T, Bhutta MF, Schilder AG, Burton MJ, Brennan-Jones CG
Cochrane Database Syst Rev 2021 Feb 4;2(2):CD013052. doi: 10.1002/14651858.CD013052.pub2. PMID: 35819801Free PMC Article
Topical versus systemic antibiotics for chronic suppurative otitis media.
Chong LY, Head K, Webster KE, Daw J, Richmond P, Snelling T, Bhutta MF, Schilder AG, Burton MJ, Brennan-Jones CG
Cochrane Database Syst Rev 2021 Feb 9;2(2):CD013053. doi: 10.1002/14651858.CD013053.pub2. PMID: 33561891Free PMC Article
Unsolved problems and new medical approaches to otitis media.
Principi N, Esposito S
Expert Opin Biol Ther 2020 Jul;20(7):741-749. Epub 2020 Apr 20 doi: 10.1080/14712598.2020.1740677. PMID: 32178551
Antibiotics versus topical antiseptics for chronic suppurative otitis media.
Head K, Chong LY, Bhutta MF, Morris PS, Vijayasekaran S, Burton MJ, Schilder AG, Brennan-Jones CG
Cochrane Database Syst Rev 2020 Jan 6;1(1):CD013056. doi: 10.1002/14651858.CD013056.pub2. PMID: 31902139Free PMC Article
Topical antibiotics for chronic suppurative otitis media.
Brennan-Jones CG, Head K, Chong LY, Burton MJ, Schilder AG, Bhutta MF
Cochrane Database Syst Rev 2020 Jan 2;1(1):CD013051. doi: 10.1002/14651858.CD013051.pub2. PMID: 31896168Free PMC Article

Prognosis

Relation between otitis media and sensorineural hearing loss: a systematic review.
Elzinga HBE, van Oorschot HD, Stegeman I, Smit AL
BMJ Open 2021 Aug 12;11(8):e050108. doi: 10.1136/bmjopen-2021-050108. PMID: 34385254Free PMC Article
Suppurative otitis media in Angola: clinical and demographic features.
Filipe M, Karppinen M, Kuatoko P, Reimer Å, Riesbeck K, Pelkonen T
Trop Med Int Health 2020 Oct;25(10):1283-1290. Epub 2020 Aug 10 doi: 10.1111/tmi.13466. PMID: 32677730
Antibiotics for prolonged wet cough in children.
Marchant JM, Petsky HL, Morris PS, Chang AB
Cochrane Database Syst Rev 2018 Jul 31;7(7):CD004822. doi: 10.1002/14651858.CD004822.pub3. PMID: 30062732Free PMC Article
Management of Chronic Suppurative Otitis Media and Otosclerosis in Developing Countries.
Master A, Wilkinson E, Wagner R
Otolaryngol Clin North Am 2018 Jun;51(3):593-605. Epub 2018 Mar 7 doi: 10.1016/j.otc.2018.01.017. PMID: 29525390
Otitis media.
Gupta BD, Singh A
Indian J Pediatr 2001 Jul;68 Suppl 3:S24-31. PMID: 11980456

Clinical prediction guides

Positive pressure therapy for Ménière's disease.
Webster KE, George B, Galbraith K, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Cochrane Database Syst Rev 2023 Feb 23;2(2):CD015248. doi: 10.1002/14651858.CD015248.pub2. PMID: 36815713Free PMC Article
Chronic suppurative otitis media causes macrophage-associated sensorineural hearing loss.
Xia A, Thai A, Cao Z, Chen X, Chen J, Bacacao B, Bekale LA, Schiel V, Bollyky PL, Maria PLS
J Neuroinflammation 2022 Sep 12;19(1):224. doi: 10.1186/s12974-022-02585-w. PMID: 36096817Free PMC Article
Topical versus systemic antibiotics for chronic suppurative otitis media.
Chong LY, Head K, Webster KE, Daw J, Richmond P, Snelling T, Bhutta MF, Schilder AG, Burton MJ, Brennan-Jones CG
Cochrane Database Syst Rev 2021 Feb 9;2(2):CD013053. doi: 10.1002/14651858.CD013053.pub2. PMID: 33561891Free PMC Article
Chronic suppurative otitis media.
Morris P
BMJ Clin Evid 2012 Aug 6;2012 PMID: 23870746Free PMC Article
Chronic suppurative otitis media.
Acuin J
BMJ Clin Evid 2007 Feb 1;2007 PMID: 19454051Free PMC Article

Recent systematic reviews

Systemic antibiotics for chronic suppurative otitis media.
Chong LY, Head K, Webster KE, Dew J, Richmond P, Snelling T, Bhutta MF, Schilder AG, Burton MJ, Brennan-Jones CG
Cochrane Database Syst Rev 2021 Feb 4;2(2):CD013052. doi: 10.1002/14651858.CD013052.pub2. PMID: 35819801Free PMC Article
Relation between otitis media and sensorineural hearing loss: a systematic review.
Elzinga HBE, van Oorschot HD, Stegeman I, Smit AL
BMJ Open 2021 Aug 12;11(8):e050108. doi: 10.1136/bmjopen-2021-050108. PMID: 34385254Free PMC Article
Topical versus systemic antibiotics for chronic suppurative otitis media.
Chong LY, Head K, Webster KE, Daw J, Richmond P, Snelling T, Bhutta MF, Schilder AG, Burton MJ, Brennan-Jones CG
Cochrane Database Syst Rev 2021 Feb 9;2(2):CD013053. doi: 10.1002/14651858.CD013053.pub2. PMID: 33561891Free PMC Article
Antibiotics versus topical antiseptics for chronic suppurative otitis media.
Head K, Chong LY, Bhutta MF, Morris PS, Vijayasekaran S, Burton MJ, Schilder AG, Brennan-Jones CG
Cochrane Database Syst Rev 2020 Jan 6;1(1):CD013056. doi: 10.1002/14651858.CD013056.pub2. PMID: 31902139Free PMC Article
Topical antibiotics for chronic suppurative otitis media.
Brennan-Jones CG, Head K, Chong LY, Burton MJ, Schilder AG, Bhutta MF
Cochrane Database Syst Rev 2020 Jan 2;1(1):CD013051. doi: 10.1002/14651858.CD013051.pub2. PMID: 31896168Free PMC Article

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