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Autoimmune process

MedGen UID:
105217
•Concept ID:
C0443146
•
Pathologic Function
Synonyms: Autoimmune Response; Autoimmune Responses
SNOMED CT: Autoimmune reaction (14848000); Autoimmune process (263680009); AI - autoimmune (263680009)

Definition

A specific humoral or cell-mediated immune response against autologous (self) antigens. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAutoimmune process

Professional guidelines

PubMed

Encephalitis: diagnosis, management and recent advances in the field of encephalitides.
Alam AM, Easton A, Nicholson TR, Irani SR, Davies NWS, Solomon T, Michael BD
Postgrad Med J 2023 Jul 21;99(1174):815-825. Epub 2022 Jun 23 doi: 10.1136/postgradmedj-2022-141812. PMID: 37490360
Autoimmune nodo-paranodopathies 10 years later: Clinical features, pathophysiology and treatment.
Uncini A
J Peripher Nerv Syst 2023 Jul;28 Suppl 3:S23-S35. doi: 10.1111/jns.12569. PMID: 37272673
Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives.
Magro-Checa C, Zirkzee EJ, Huizinga TW, Steup-Beekman GM
Drugs 2016 Mar;76(4):459-83. doi: 10.1007/s40265-015-0534-3. PMID: 26809245Free PMC Article

Recent clinical studies

Etiology

An update on the pathogenesis of Hashimoto's thyroiditis.
Weetman AP
J Endocrinol Invest 2021 May;44(5):883-890. Epub 2020 Dec 17 doi: 10.1007/s40618-020-01477-1. PMID: 33332019Free PMC Article
Cardiac Autoimmunity: Myocarditis.
Bracamonte-Baran W, Čiháková D
Adv Exp Med Biol 2017;1003:187-221. doi: 10.1007/978-3-319-57613-8_10. PMID: 28667560Free PMC Article
Novel aspects of pathogenesis and regeneration mechanisms in COPD.
Bagdonas E, Raudoniute J, Bruzauskaite I, Aldonyte R
Int J Chron Obstruct Pulmon Dis 2015;10:995-1013. Epub 2015 Jun 2 doi: 10.2147/COPD.S82518. PMID: 26082624Free PMC Article
Autoimmune thyroid disorders.
Antonelli A, Ferrari SM, Corrado A, Di Domenicantonio A, Fallahi P
Autoimmun Rev 2015 Feb;14(2):174-80. Epub 2014 Oct 25 doi: 10.1016/j.autrev.2014.10.016. PMID: 25461470
Type 1 diabetes: pathogenesis and prevention.
Gillespie KM
CMAJ 2006 Jul 18;175(2):165-70. doi: 10.1503/cmaj.060244. PMID: 16847277Free PMC Article

Diagnosis

IgA Nephropathy: An Interesting Autoimmune Kidney Disease.
Rajasekaran A, Julian BA, Rizk DV
Am J Med Sci 2021 Feb;361(2):176-194. Epub 2020 Oct 8 doi: 10.1016/j.amjms.2020.10.003. PMID: 33309134Free PMC Article
Autoimmune gastritis.
Lenti MV, Rugge M, Lahner E, Miceli E, Toh BH, Genta RM, De Block C, Hershko C, Di Sabatino A
Nat Rev Dis Primers 2020 Jul 9;6(1):56. doi: 10.1038/s41572-020-0187-8. PMID: 32647173
Polyglandular autoimmune syndromes.
Kahaly GJ, Frommer L
J Endocrinol Invest 2018 Jan;41(1):91-98. Epub 2017 Aug 17 doi: 10.1007/s40618-017-0740-9. PMID: 28819917
Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives.
Magro-Checa C, Zirkzee EJ, Huizinga TW, Steup-Beekman GM
Drugs 2016 Mar;76(4):459-83. doi: 10.1007/s40265-015-0534-3. PMID: 26809245Free PMC Article
Sjögren's syndrome.
Fox RI
Lancet 2005 Jul 23-29;366(9482):321-31. doi: 10.1016/S0140-6736(05)66990-5. PMID: 16039337

Therapy

Thymectomy in myasthenia gravis.
Rath J, Moser B, Zimprich F
Curr Opin Neurol 2023 Oct 1;36(5):416-423. Epub 2023 Jul 25 doi: 10.1097/WCO.0000000000001189. PMID: 37639450
Alopecia areata: a review of disease pathogenesis.
Rajabi F, Drake LA, Senna MM, Rezaei N
Br J Dermatol 2018 Nov;179(5):1033-1048. Epub 2018 Sep 9 doi: 10.1111/bjd.16808. PMID: 29791718
Cardiac Autoimmunity: Myocarditis.
Bracamonte-Baran W, Čiháková D
Adv Exp Med Biol 2017;1003:187-221. doi: 10.1007/978-3-319-57613-8_10. PMID: 28667560Free PMC Article
Management of Neuropsychiatric Systemic Lupus Erythematosus: Current Approaches and Future Perspectives.
Magro-Checa C, Zirkzee EJ, Huizinga TW, Steup-Beekman GM
Drugs 2016 Mar;76(4):459-83. doi: 10.1007/s40265-015-0534-3. PMID: 26809245Free PMC Article
Herpesviruses and autoimmunity.
Posnett DN
Curr Opin Investig Drugs 2008 May;9(5):505-14. PMID: 18465661

Prognosis

Thymectomy in myasthenia gravis.
Rath J, Moser B, Zimprich F
Curr Opin Neurol 2023 Oct 1;36(5):416-423. Epub 2023 Jul 25 doi: 10.1097/WCO.0000000000001189. PMID: 37639450
Tuberculosis and autoimmunity: Common features.
Starshinova A, Malkova А, Kudryavtsev I, Kudlay D, Zinchenko Y, Yablonskiy P
Tuberculosis (Edinb) 2022 May;134:102202. Epub 2022 Apr 4 doi: 10.1016/j.tube.2022.102202. PMID: 35430551
Cardiac Autoimmunity: Myocarditis.
Bracamonte-Baran W, Čiháková D
Adv Exp Med Biol 2017;1003:187-221. doi: 10.1007/978-3-319-57613-8_10. PMID: 28667560Free PMC Article
Novel aspects of pathogenesis and regeneration mechanisms in COPD.
Bagdonas E, Raudoniute J, Bruzauskaite I, Aldonyte R
Int J Chron Obstruct Pulmon Dis 2015;10:995-1013. Epub 2015 Jun 2 doi: 10.2147/COPD.S82518. PMID: 26082624Free PMC Article
Vogt-Koyanagi-Harada syndrome.
Greco A, Fusconi M, Gallo A, Turchetta R, Marinelli C, Macri GF, De Virgilio A, de Vincentiis M
Autoimmun Rev 2013 Sep;12(11):1033-8. Epub 2013 Apr 6 doi: 10.1016/j.autrev.2013.01.004. PMID: 23567866

Clinical prediction guides

Thymectomy in myasthenia gravis.
Rath J, Moser B, Zimprich F
Curr Opin Neurol 2023 Oct 1;36(5):416-423. Epub 2023 Jul 25 doi: 10.1097/WCO.0000000000001189. PMID: 37639450
Tuberculosis and autoimmunity: Common features.
Starshinova A, Malkova А, Kudryavtsev I, Kudlay D, Zinchenko Y, Yablonskiy P
Tuberculosis (Edinb) 2022 May;134:102202. Epub 2022 Apr 4 doi: 10.1016/j.tube.2022.102202. PMID: 35430551
Interferons and other cytokines, genetics and beyond in COVID-19 and autoimmunity.
Opdenakker G, Van Damme J
Cytokine Growth Factor Rev 2021 Apr;58:134-140. Epub 2021 Jan 29 doi: 10.1016/j.cytogfr.2021.01.004. PMID: 33563543Free PMC Article
Sjögren syndrome and MIG.
Ruffilli I
Clin Ter 2019 Nov-Dec;170(6):e478-e482. doi: 10.7417/CT.2019.2179. PMID: 31696913
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.
International Multiple Sclerosis Genetics Consortium
Science 2019 Sep 27;365(6460) doi: 10.1126/science.aav7188. PMID: 31604244Free PMC Article

Recent systematic reviews

Blood tests as biomarkers for the diagnosis and prognosis of sudden sensorineural hearing loss in adults: a systematic review.
Al-Azzawi A, Stapleton E
J Laryngol Otol 2023 Sep;137(9):977-984. Epub 2023 Feb 16 doi: 10.1017/S0022215123000282. PMID: 36794400
Hidradenitis Suppurativa and Thyroid Disease: Systematic Review and Meta-Analysis.
Phan K, Huo YR, Charlton O, Smith SD
J Cutan Med Surg 2020 Jan/Feb;24(1):23-27. Epub 2019 Sep 5 doi: 10.1177/1203475419874411. PMID: 31994934
A role for autoantibodies in atherogenesis.
Iseme RA, McEvoy M, Kelly B, Agnew L, Walker FR, Handley T, Oldmeadow C, Attia J, Boyle M
Cardiovasc Res 2017 Aug 1;113(10):1102-1112. doi: 10.1093/cvr/cvx112. PMID: 28899001
Vogt-Koyanagi-Harada syndrome.
Greco A, Fusconi M, Gallo A, Turchetta R, Marinelli C, Macri GF, De Virgilio A, de Vincentiis M
Autoimmun Rev 2013 Sep;12(11):1033-8. Epub 2013 Apr 6 doi: 10.1016/j.autrev.2013.01.004. PMID: 23567866
Diabetes: glycaemic control in type 1.
Leelarathna L, Guzder R, Muralidhara K, Evans ML
BMJ Clin Evid 2011 May 9;2011 PMID: 21549022Free PMC Article

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