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Enlarged distal tibial epiphysis

MedGen UID:
1052477
•Concept ID:
CN378032
•
Finding
Synonym: Large distal tibial epiphysis
 
HPO: HP:6000886

Definition

Size (volume) of the distal epiphysis of the tiba above the upper limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnlarged distal tibial epiphysis

Professional guidelines

PubMed

Alterations of growth plate and abnormal insulin-like growth factor I metabolism in growth-retarded hypokalemic rats: effect of growth hormone treatment.
Gil-Peña H, Garcia-Lopez E, Alvarez-Garcia O, Loredo V, Carbajo-Perez E, Ordoñez FA, Rodriguez-Suarez J, Santos F
Am J Physiol Renal Physiol 2009 Sep;297(3):F639-45. Epub 2009 Jul 8 doi: 10.1152/ajprenal.00188.2009. PMID: 19587145

Recent clinical studies

Therapy

Growth plate abnormalities in pediatric cancer patients undergoing phase 1 anti-angiogenic therapy: a report from the Children's Oncology Group Phase I Consortium.
Voss SD, Glade-Bender J, Spunt SL, DuBois SG, Widemann BC, Park JR, Leary SE, Nelson MD, Adamson PC, Blaney SM, Weigel B
Pediatr Blood Cancer 2015 Jan;62(1):45-51. Epub 2014 Sep 24 doi: 10.1002/pbc.25229. PMID: 25257751Free PMC Article
Alterations of growth plate and abnormal insulin-like growth factor I metabolism in growth-retarded hypokalemic rats: effect of growth hormone treatment.
Gil-Peña H, Garcia-Lopez E, Alvarez-Garcia O, Loredo V, Carbajo-Perez E, Ordoñez FA, Rodriguez-Suarez J, Santos F
Am J Physiol Renal Physiol 2009 Sep;297(3):F639-45. Epub 2009 Jul 8 doi: 10.1152/ajprenal.00188.2009. PMID: 19587145

Prognosis

Hypertrophy Associated With Vascular Malformations: Analysis of Growth and Results of Epiphysiodesis.
Borowski A, Bajelidze G, Bowen JR
Orthopedics 2018 Jul 1;41(4):e574-e579. Epub 2017 Dec 19 doi: 10.3928/01477447-20171213-07. PMID: 29257190
Growth plate abnormalities in pediatric cancer patients undergoing phase 1 anti-angiogenic therapy: a report from the Children's Oncology Group Phase I Consortium.
Voss SD, Glade-Bender J, Spunt SL, DuBois SG, Widemann BC, Park JR, Leary SE, Nelson MD, Adamson PC, Blaney SM, Weigel B
Pediatr Blood Cancer 2015 Jan;62(1):45-51. Epub 2014 Sep 24 doi: 10.1002/pbc.25229. PMID: 25257751Free PMC Article
Epiphyseal ossification centers in the assessment of fetal maturity: sonographic correlation with the amniocentesis lung profile.
Mahony BS, Bowie JD, Killam AP, Kay HH, Cooper C
Radiology 1986 May;159(2):521-4. doi: 10.1148/radiology.159.2.3515425. PMID: 3515425

Clinical prediction guides

A Chinese case of CHST3-related skeletal dysplasia and a systematic review.
Liang H, Qi W, Jin C, Pang Q, Cui L, Jiang Y, Wang O, Li M, Xing X, Liu W, Xia W
Endocrine 2023 Jun;80(3):658-668. Epub 2023 Feb 2 doi: 10.1007/s12020-023-03303-z. PMID: 36729370
Postoperative radiographic observations following transphyseal anterior cruciate ligament reconstruction in skeletally immature patients.
Smoak JB, Macfarlane A, Kluczynski MA, Ferrick MR, Doak JP, Bisson LJ, Marzo JM
Skeletal Radiol 2020 Jun;49(6):861-868. Epub 2019 Dec 17 doi: 10.1007/s00256-019-03361-3. PMID: 31848655
Exogenous C-type natriuretic peptide restores normal growth and prevents early growth plate closure in its deficient rats.
Hirota K, Furuya M, Morozumi N, Yoshikiyo K, Yotsumoto T, Jindo T, Nakamura R, Murakami K, Ueda Y, Hanada T, Sade H, Yoshida S, Enomoto K, Kanai Y, Yamauchi I, Yamashita T, Ueda-Sakane Y, Fujii T, Yasoda A, Inagaki N
PLoS One 2018;13(9):e0204172. Epub 2018 Sep 20 doi: 10.1371/journal.pone.0204172. PMID: 30235256Free PMC Article
Hypertrophy Associated With Vascular Malformations: Analysis of Growth and Results of Epiphysiodesis.
Borowski A, Bajelidze G, Bowen JR
Orthopedics 2018 Jul 1;41(4):e574-e579. Epub 2017 Dec 19 doi: 10.3928/01477447-20171213-07. PMID: 29257190
The influence of relative body breadth on the diaphyseal morphology of the human lower limb.
Davies TG, Stock JT
Am J Hum Biol 2014 Nov-Dec;26(6):822-35. Epub 2014 Aug 28 doi: 10.1002/ajhb.22606. PMID: 25163696

Recent systematic reviews

A Chinese case of CHST3-related skeletal dysplasia and a systematic review.
Liang H, Qi W, Jin C, Pang Q, Cui L, Jiang Y, Wang O, Li M, Xing X, Liu W, Xia W
Endocrine 2023 Jun;80(3):658-668. Epub 2023 Feb 2 doi: 10.1007/s12020-023-03303-z. PMID: 36729370

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